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Investigation of the radioprotective properties of some tea polyphenols

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Abstract

The influence of tea and coffee flavonoids (−)-epicatechin (EC) and (+)-catechin (C) on the effect of γ-irradiation of DNA molecules in solutions was investigated. The concentrations of these and other components in different samples of black and green tea were analyzed by the capillary electrophoresis. It was determined from the experimental data obtained by different methods (circular dichroism and UV spectra, viscosimetry and optical investigations) that C and EC do not form complexes with DNA in solutions. It was shown that C and EC have radioprotective properties, being scavengers of the water radiolysis products.

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Authors and Affiliations

  1. Faculty of Physics, St. Petersburg State University, Ulyanovskaya, 3, 198504, St. Petersburg, Russia

    D. S. Ershov, S. V. Paston & N. A. Kasyanenko

  2. Faculty of Chemistry, St. Petersburg State University, Universitetsky prosp., 26, 198504, St. Petersburg, Russia

    L. A. Kartsova, A. V. Alekseeva & O. V. Ganzha

Authors
  1. D. S. Ershov
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  2. S. V. Paston
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  3. L. A. Kartsova
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  4. A. V. Alekseeva
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  5. O. V. Ganzha
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  6. N. A. Kasyanenko
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Corresponding author

Correspondence to S. V. Paston.

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Ershov, D.S., Paston, S.V., Kartsova, L.A. et al. Investigation of the radioprotective properties of some tea polyphenols. Struct Chem 22, 475–482 (2011). https://doi.org/10.1007/s11224-011-9765-4

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  • DOI: https://doi.org/10.1007/s11224-011-9765-4

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