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Synthesis, Spectral and Structural Study of N-[1-(N,N,N′,N′-Tetramethylphosphoramidoyl)- 1H-Benzimidazol-2-yl]-Propionimidic Ethyl Ether

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Abstract

The preparation of N-[1-(N,N,N′,N′-tetramethylphosphoramidoyl)-1H-benzimidazol-2-yl]-proponimidic ethyl ester 2 has been achieved by the reaction of N-(1H-benzimidazol-2-yl)-proponimidic acid ethyl ester 1 with N,N,N′,N′-tetramethylchlorophosphoramide. The structure of compound 2 has been determined by X-ray diffraction. The results of (1H, 13C, 31P) NMR, IR, EI-MS spectral data are consistent with those obtained from the X-ray diffraction. The compound crystallizes in the triclinic system, following the EsZ conformation. In the crystal, there are two weak C3–H3⋅s1 and C15–H15⋅sO1 intermolecular hydrogen bonds.

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Authors and Affiliations

  1. Laboratoire Chimie Analytique et Electrochimie, Faculté des Sciences de Tunis, Campus Universitaire, Tunis El-Manar, 2092, Tunisie

    N. Raouafi, K. Boujlel & M. L. BenKhoud

  2. Institut für Anorganische und Analytische Chemie, Technische Universität Braunschweig, Braunschweig, 38023, Germany

    M. Freytag & P. G. Jones

Authors
  1. N. Raouafi
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  2. M. Freytag
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  3. P. G. Jones
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  4. K. Boujlel
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  5. M. L. BenKhoud
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Correspondence to N. Raouafi.

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Raouafi, N., Freytag, M., Jones, P.G. et al. Synthesis, Spectral and Structural Study of N-[1-(N,N,N′,N′-Tetramethylphosphoramidoyl)- 1H-Benzimidazol-2-yl]-Propionimidic Ethyl Ether. Struct Chem 16, 169–172 (2005). https://doi.org/10.1007/s11224-005-2848-3

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  • DOI: https://doi.org/10.1007/s11224-005-2848-3

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