Abstract
Zinc enolates obtained from methyl 4-bromo-2,2-dimethyl-3-oxo-4-phenylbutanoates and zinc react with aromatic aldehydes to form 6-aryl-3,3-dimethyl-5-phenyl-2,3,5,6-tetrahydropyran-2,4-diones as a single geometric isomer.
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REFERENCES
Izawa, T. and Mukaiyama, T., Chem. Lett., 1975, no. 2, p. 161.
Kende, A.S., Liu, K., Kaldor, I., Dorey, G., and Koch, K., J. Am. Chem. Soc., 1995, vol. 117, no.31, p. 8258.
Tait, B.D., Hagen, S., Domagala, J., Ellsworth. E.L., Gajda, C., Hamilton, H., Vara, P.J.V.N., Ferguson, D., Graham, N., Hupe, D., Nouhan, C., Tummino, P.J., Humblet, C., Lunney, E.A., Pavlovsky, A., Rubin, J., Grachek, S.J., Baldwin, E.T., Bhat, T.N., Erickson, J.W., Gulnik, S.V., and Liu, B., J. Med. Chem., 1997, vol. 40, no.23, p. 3781.
Hagiwara, H. and Uda, H., J. Chem. Soc., Perkin Trans. 1, 1985, no. 6, p. 1157.
Kashihara, H., Shinoki, H., and Suemune, H., Chem. Pharm. Bull., 1986, vol. 34, no.11, p. 4527.
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Translated from Zhurnal Obshchei Khimii, Vol. 75, No. 9, 2005, pp. 1528–1530.
Original Russian Text Copyright © 2005 by Shchepin, Russkikh, Sazhneva, Vakhrin.
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Shchepin, V.V., Russkikh, N.Y., Sazhneva, Y.K. et al. Synthesis of 6-Aryl-3,3-dimethyl-5-phenyl-2,3,5,6-tetrahydropyran-2,4-diones. Russ J Gen Chem 75, 1455–1457 (2005). https://doi.org/10.1007/s11176-005-0445-1
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DOI: https://doi.org/10.1007/s11176-005-0445-1