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Recognition of the Protonation Model of a Double-Stranded Polyribonucleic Acid by Spectrometry Data

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Abstract

Simulated and experimental multivariate dependences observed on spectrometric acid-base titration of polyribonucleic acid were examined. Examination of the simulated data revealed the possibility for differentiating distribution diagrams of polymer species produced by complex formation with single- and double-stranded infinite polymers under conditions of incomplete concentration and spectral selectivity. The protonation constants of polycytidylic polyribonucleic acid were calculated from experimental data by using the developed chemometric procedure.

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Authors and Affiliations

  1. St. Petersburg State University, St. Petersburg, Russia

    A. G. Kudrev

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  1. A. G. Kudrev
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__________

Translated from Zhurnal Obshchei Khimii, Vol. 75, No. 8, 2005, pp. 1388–1395.

Original Russian Text Copyright © 2005 by Kudrev.

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Kudrev, A.G. Recognition of the Protonation Model of a Double-Stranded Polyribonucleic Acid by Spectrometry Data. Russ J Gen Chem 75, 1318–1324 (2005). https://doi.org/10.1007/s11176-005-0417-5

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  • DOI: https://doi.org/10.1007/s11176-005-0417-5

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