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Radiation stability of carboxymethylcellulose microgels cross-linked by copper ions

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Abstract

Carboxymethylcellulose (CMC) complexes cross-linked with copper ions exhibit radiation stability, up to high doses of radiation (∼2000 Gy). A model estimate of the exit of copper ions from the CMC—Cu complexes, in which CMC can be a radionuclide (67Cu2+) carrier, showed that the dose load on the body does not increase for the calculated estimate of the real medical dose (∼750 Gy).

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Authors and Affiliations

  1. Department of Chemistry, Lomonosov Moscow State University, Build. 3, 1 Leninskie Gory, 119991, Moscow, Russian Federation

    M. A. Orlova, T. P. Trofimova, A. S. Zolotova, A. A. Larenkov, A. P. Orlov & V. V. Spiridonov

  2. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, 1 ul. Ostrovityanova, 117997, Moscow, Russian Federation

    M. A. Orlova

  3. Institute of Physiologically Active Compounds, Russian Academy of Sciences, 1 Severnyi proezd, 142432, Chernogolovka, Moscow Region, Russian Federation

    T. P. Trofimova

  4. V. I. Vernadsky Institute of Geochemistry and Analytical Chemistry, Russian Academy of Sciences, 19 ul. Kosygina, 119334, Moscow, Russian Federation

    A. A. Borodkov

Authors
  1. M. A. Orlova
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  2. T. P. Trofimova
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  3. A. S. Zolotova
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  4. A. A. Larenkov
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  5. A. P. Orlov
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  6. A. A. Borodkov
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  7. V. V. Spiridonov
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Corresponding author

Correspondence to M. A. Orlova.

Additional information

No human or animal subjects were used in this research.

The authors declare no competing interests.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2515–2518, November, 2022.

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Orlova, M.A., Trofimova, T.P., Zolotova, A.S. et al. Radiation stability of carboxymethylcellulose microgels cross-linked by copper ions. Russ Chem Bull 71, 2515–2518 (2022). https://doi.org/10.1007/s11172-022-3681-1

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  • DOI: https://doi.org/10.1007/s11172-022-3681-1

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