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Chelate synthesis of 1,6-naphthyridin-4-ones

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Abstract

An efficient synthesis of novel functionalized 1,6-naphthyridin-4-ones is based on cyclization of difluoroboron chelate complexes of 1-alkyl-N′-benzoyl-2-methyl-4-oxo-1,4-dihydro-pyridine-3-carboximidamide under the action of dimethylformamide dimethyl acetal or sodium alkoxide.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    M. A. Present, S. V. Baranin & Yu. N. Bubnov

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  1. M. A. Present
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  2. S. V. Baranin
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  3. Yu. N. Bubnov
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Correspondence to S. V. Baranin.

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Dedicated to Academician of the Russian Academy of Sciences V. N. Charushin on the occasion of his 70th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1006–1009, May, 2021.

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Present, M.A., Baranin, S.V. & Bubnov, Y.N. Chelate synthesis of 1,6-naphthyridin-4-ones. Russ Chem Bull 70, 1006–1009 (2021). https://doi.org/10.1007/s11172-021-3181-8

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  • DOI: https://doi.org/10.1007/s11172-021-3181-8

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