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Cytotoxic activity of silver nanocomposites based on N, N-diallyl-N′-acylhydrazines copolymers

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Abstract

Silver nanocomposites based on copolymers of N, N-diallyl-N′-acylhydrazines (DAH) with acrylic acid, methacrylic acid, and acrylamide have been developed. They exhibit cytotoxic activity against melanoma MS and rhabdomyosarcoma RD.

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Correspondence to M. N. Gorbunova.

Additional information

The authors are grateful to the Center for Collective Use of the Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences “Research of Materials and Substances” for spectral, analytical and biological studies.

The work was financially supported by the Russian Foundation for Basic Research and Government of Perm Krai (Project No. 19-43-590019-p_a).

This paper does not contain descriptions of studies on animals or humans.

The authors declare no competing interests.

Based on the materials of the IV International Conference “Modern Synthetic Methodologies for Creating Medicines and Functional Materials” (November 16–20, 2019, Ekaterinburg, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 469–474, March, 2021.

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Gorbunova, M.N., Voronina, A.O. & Strelnikov, V.N. Cytotoxic activity of silver nanocomposites based on N, N-diallyl-N′-acylhydrazines copolymers. Russ Chem Bull 70, 469–474 (2021). https://doi.org/10.1007/s11172-021-3110-x

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  • DOI: https://doi.org/10.1007/s11172-021-3110-x

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