Abstract
New nickel- and palladium-containing catalysts for reductive N-alkylation of α-alanyl-α-proline dipeptide with ethyl 2-oxo-4-phenylbutanoate have been investigated. Based on the empirical data obtained, the optimal scheme for the catalytic synthesis of enalapril was proposed.
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Russian Chemical Bulletin, International Edition, Vol. 69, No. 10, pp. 1923–1927, October, 2020
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1923–1927, October, 2020.
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Abdullaev, M.G. Hydrogenation N-alkylation of α-alanyl-α-proline with ethyl 2-oxo-4-phenylbutanoate on organometallic catalysts. Russ Chem Bull 69, 1923–1927 (2020). https://doi.org/10.1007/s11172-020-2979-0
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DOI: https://doi.org/10.1007/s11172-020-2979-0