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3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors

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Abstract

3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) were synthesized by either nucleophilic substitution of the bromine atoms of parent 3,3-bis(2- bromoethyl) compounds or nitration of structurally related 3,3-bis(2-hydroxyethyl) derivatives. The synthesized compounds comprise two different NO donating moieties, namely, oxytriaz- 1-ene 2-oxide and nitrate groups, and, therefore, can be regarded as a new type of NO-donating agents.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    G. V. Pokhvisneva, P. B. Gordeev, S. V. Nikitin, G. A. Smirnov, T. V. Ternikova & O. A. Luk’yanov

Authors
  1. G. V. Pokhvisneva
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  2. P. B. Gordeev
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  3. S. V. Nikitin
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  4. G. A. Smirnov
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  5. T. V. Ternikova
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  6. O. A. Luk’yanov
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Corresponding author

Correspondence to G. V. Pokhvisneva.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1655–1661, September, 2018.

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Pokhvisneva, G.V., Gordeev, P.B., Nikitin, S.V. et al. 3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors. Russ Chem Bull 67, 1655–1661 (2018). https://doi.org/10.1007/s11172-018-2273-6

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  • DOI: https://doi.org/10.1007/s11172-018-2273-6

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