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Ring-ring isomerization in the series of N-(carbamoyl)-1-aryl-2,3,4,5,6,7-hexahydro-3-hydroxy-6,6-dimethyl-2,4-dioxo-1H-indole-3-carboxamides

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Abstract

N-(Carbamoyl)-1-aryl-2,3,4,5,6,7-hexahydro-3-hydroxy-6,6-dimethyl-2,4-dioxo-1H-indole-3-carboxamides upon dissolution in DMSO or DMF undergo a reversible isomerization to 5-(2-arylamino-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-triones.

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Authors and Affiliations

  1. Research Institute of Physical and Organic Chemistry, Southern Federal University, 194/2 prosp. Stachki, 344090, Rostov on Don, Russian Federation

    G. S. Borodkin, S. B. Zaichenko, I. G. Borodkina, L. V. Belousova & L. Yu. Ukhin

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  1. G. S. Borodkin
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  2. S. B. Zaichenko
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  3. I. G. Borodkina
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  4. L. V. Belousova
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  5. L. Yu. Ukhin
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Correspondence to L. Yu. Ukhin.

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Dedicated to Academician of the Russian Academy of Sciences V. I. Minkin on the occasion of his 80th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 0664—0667, March, 2015.

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Borodkin, G.S., Zaichenko, S.B., Borodkina, I.G. et al. Ring-ring isomerization in the series of N-(carbamoyl)-1-aryl-2,3,4,5,6,7-hexahydro-3-hydroxy-6,6-dimethyl-2,4-dioxo-1H-indole-3-carboxamides. Russ Chem Bull 64, 664–667 (2015). https://doi.org/10.1007/s11172-015-0915-5

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  • DOI: https://doi.org/10.1007/s11172-015-0915-5

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