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Effect of dimethyl sulfoxide on electrochemical and antiradical properties of ascorbic acid

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Abstract

Solvent effect of dimethyl sulfoxide (DMSO) on the oxidation-reduction properties of ascorbic acid (AA) was studied by the electroanalytical method of differential pulse voltammetry (DPV) in a three-electrode cell at 37 °C. Dimethylsulfoxide was found to considerably decrease the oxidation ability of AA due to the formation of molecular complexes between AA and DMSO through the intermolecular hydrogen bonds and shift the anodic peak potential toward the positive values, with its intensity being decreased. Kinetic spectrophotometric measurements in the UV-vis regions of the reaction of the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH·) with AA confirmed the stabilizing effect of the Lewis base DMSO on the reactivity of the neutral form of AA and its intermediates with respect to DPPH·. The mechanism of oxidation of AA with the radical DPPH· in the presence of DMSO was considered.

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References

  1. Q. Sheng, H. Yu, J. Zheng, J. Elecroanal. Chem., 2007, 606, 39.

    Article  CAS  Google Scholar 

  2. G. P. Jin, Q. Z. Chen, Y. F. Ding, J. B. He, Electrochim. Acta, 2007, 52, 2535.

    Article  CAS  Google Scholar 

  3. S. Yilmaz, M. Sadikoglu, G. Saglikoglu, S. Yagmur, G. Askin, Int. J. Elecrochem. Sci., 2008, 3, 1534.

    CAS  Google Scholar 

  4. P. Molyneux, Songklanakarin J. Sci. Technol., 2004, 26, 211.

    CAS  Google Scholar 

  5. E. N. Hristea, M. T. Caproiu, G. Pencu, M. Hillebrand, T. Consantinescu, A. T. Balaban, Int. J. Mol. Sci., 2006, 7, 130.

    Article  CAS  Google Scholar 

  6. G. C. Yen, P. D. Duh, H. L. Tsai, Food Chem., 2002, 79, 307.

    Article  CAS  Google Scholar 

  7. L. S. Limaye, Stem Cells, 1997, 15, 353.

    Article  CAS  Google Scholar 

  8. S. A. Markarian, S. Bonora, K. A. Bagramyan, V. B. Arakelyan, Cryobiology, 2004, 49, 1.

    Article  CAS  Google Scholar 

  9. S. W. Jacob, R. Herschler, Cryobiology, 1986, 23, 14.

    Article  CAS  Google Scholar 

  10. Z. W. Yu, P. J. Quinn, Biosci. Rep., 1994, 14, 259.

    Article  CAS  Google Scholar 

  11. A. L. Zatikyan, E. A. Kazoyan, S. Bonora, Sh. A. Markaryan, Zh. Prikl. Spektroskopii, 2008, 75, 653 [J. Appl. Spectr. (Engl. Transl.), 2008, 75].

    Google Scholar 

  12. Sh. A. Markaryan, A. R. Sarkisyan, Zh. Prikl. Spektroskopii, 2011, 78, 11 [J. Appl. Spectr. (Engl. Transl.), 2011, 78].

    Google Scholar 

  13. E. A. Kazoyan, A. M. Terzyan, Sh. A. Markaryan, Zh. Fiz. Khim., 2011, 85, 689 [Russ. J. Phys. Chem. (Engl. Transl.), 2011, 85].

    Google Scholar 

  14. S. A. Markarian, L. S. Gabrielyan, J. Mol. Liq., 2011, 164, 207.

    Article  CAS  Google Scholar 

  15. L. A. Tavadyan, K. A. Galoian, L. A. Harutunyan, H. G. Tonikyan, A. A. Galoyan, Neurochem Res., 2010, 35, 947.

    Article  CAS  Google Scholar 

  16. S. H. Minasyan, L. A. Tavadyan, A. A. Khachoyan, A. P. Antonyan, H. G. Davtyan, M. A. Parsadanyan, P. O. Vardevanyan, Bioelectrochemistry, 2006, 68, 48.

    Article  CAS  Google Scholar 

  17. G. R. Buettner, J. Biochem. Biophys. Methods, 1988, 16, 27.

    Article  CAS  Google Scholar 

  18. W. Bors, G. R. Buettner, The Vitamin C Radical and its Reactions in Vitamin C in Health and Disease, Eds L. Parker, J. Fuchs, Marcel Dekker, Inc., New York, 1997, p. 75.

  19. http://en.wikipedia.org/wiki/Acid-dissociation-constant#cite-not-23.

  20. M. H. Abraham, P. L. Grelier, D. V. Prior, J. J. Morris, P. J. Taylor, J. Chem. Soc., Perkin Trans. 2, 1990, 2, 521.

    Article  Google Scholar 

  21. D. Huang, B. Ou, R. L. Prior, J. Agric. Food Chem., 2005, 53, 1841.

    Article  CAS  Google Scholar 

  22. W. Brand-Williams, M. E. Cuvelier, C. Berset, Lebensmittel-Wissenschaft und Technologie/Food Sci. Technol., 1995, 28, 25.

    CAS  Google Scholar 

  23. A. Mohajeri, S. Somayeh Asemani, J. Mol. Struct., 2009, 930, 15.

    Article  CAS  Google Scholar 

  24. M. H. Pournaghi-Azar, R. Ojani, Talanta, 1995, 42, 1839.

    Article  CAS  Google Scholar 

  25. L. Valgimigli, J. T. Banks, K. U. Ingold, K. U. Lusztik, J. Am. Chem. Soc., 1995, 117, 9966.

    Article  CAS  Google Scholar 

  26. L. A. Tavadyan, V. A. Mardoyan, A. B. Nalbandyan, Khim. fizika [Chem. Physics], 1986, 5, 1377 (in Russian).

    CAS  Google Scholar 

  27. P. Gaikwad, A. Barik, K. I. Priyadarsini, B. S. M. Rao, Res. Chem. Intermed., 2010, 36, 1065.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Yerevan State University, 1 ul. Al. Manukyana, 0025, Yerevan, Republic of Armenia

    Sh. A. Markaryan & G. A. Shahinyan

  2. A. B. Nalbandyan Institute of Chemical Physics, National Academy of Science of Republic of Armenia, 5/2 ul. P. Sevaka, 0014, Yerevan, Republic of Armenia

    L. A. Tavadyan & G. G. Kocharyan

Authors
  1. Sh. A. Markaryan
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  2. L. A. Tavadyan
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  3. G. G. Kocharyan
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  4. G. A. Shahinyan
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Correspondence to Sh. A. Markaryan.

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According to the materials of the Conference “Oxidation, oxidation stress, and antioxidants” (October 9–12, 2012, Yerevan (Republic of Armenia)).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1625–1629, July, 2013.

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Markaryan, S.A., Tavadyan, L.A., Kocharyan, G.G. et al. Effect of dimethyl sulfoxide on electrochemical and antiradical properties of ascorbic acid. Russ Chem Bull 62, 1625–1629 (2013). https://doi.org/10.1007/s11172-013-0235-6

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  • DOI: https://doi.org/10.1007/s11172-013-0235-6

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