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Synthesis of derivatives of 4-amino-2-trifluoromethylnicotinic acid

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Abstract

The method for the synthesis of ethyl 4-R-amino-2-trifluoromethylnicotinates from a diphenylboron complex of ethyl 2-acetyl-3-amino-4,4,4-trifluorobut-2-enoate was developed.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    L. S. Vasil’ev, F. E. Surzhikov & V. A. Dorokhov

Authors
  1. L. S. Vasil’ev
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  2. F. E. Surzhikov
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  3. V. A. Dorokhov
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2221–2223, October, 2004.

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Vasil’ev, L.S., Surzhikov, F.E. & Dorokhov, V.A. Synthesis of derivatives of 4-amino-2-trifluoromethylnicotinic acid. Russ Chem Bull 53, 2319–2321 (2004). https://doi.org/10.1007/s11172-005-0120-z

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  • DOI: https://doi.org/10.1007/s11172-005-0120-z

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