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New approach to the synthesis of 2-alkylsulfanyl-4,5,6-trimethylnicotinonitriles

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Abstract

Multicomponent condensation of acetaldehyde, cyanothioacetamide, 1-(but-2-en-2-yl)pyrrolidine, and alkyl halides afforded 2-alkylsulfanyl-4,5,6-trimethylnicotinonitriles. Their structure was confirmed by IR, 1H NMR spectroscopy, and chromatography-mass spectrometry.

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Authors and Affiliations

  1. Shevchenko Lugansk University, ul. Oboronnaya 2, Lugansk, 91011, Ukraine

    I. V. Dyachenko & V. D. Dyachenko

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  1. I. V. Dyachenko
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  2. V. D. Dyachenko
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Correspondence to I. V. Dyachenko.

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Original Russian Text © I.V. Dyachenko, V.D. Dyachenko, 2015, published in Zhurnal Obshchei Khimii, 2015, Vol. 85, No. 7, pp. 1146–1151.

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Dyachenko, I.V., Dyachenko, V.D. New approach to the synthesis of 2-alkylsulfanyl-4,5,6-trimethylnicotinonitriles. Russ J Gen Chem 85, 1668–1672 (2015). https://doi.org/10.1134/S1070363215070166

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  • DOI: https://doi.org/10.1134/S1070363215070166

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