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Iron-catalyzed highly efficient aerobic oxidative synthesis of benzimidazoles direct from oximes in water

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Abstract

This article presents a general and efficient method for aerobic oxidative synthesis of benzimidazoles from oximes catalyzed by Fe(NO3)3·9H2O under air in water. This practical method uses air as an economic and green oxidant, water as a green solvent, and tolerates a wide range of substrates that can afford the target benzimidazoles in moderate to good yields.

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  1. Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, 210094, China

    Jiatao Yu & Ming Lu

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  1. Jiatao Yu
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Correspondence to Jiatao Yu.

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Yu, J., Lu, M. Iron-catalyzed highly efficient aerobic oxidative synthesis of benzimidazoles direct from oximes in water. Res Chem Intermed 42, 471–479 (2016). https://doi.org/10.1007/s11164-015-2031-4

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