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Four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium carbonate

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Abstract

A new and efficient one-pot synthesis of dihydropyridones derivatives by four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium carbonate is described. The reactions were performed in water and ethanol under reflux conditions and afforded high yields of products.

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Acknowledgments

We gratefully acknowledge financial support from the Research Council of Islamic Azad University of Yazd of Iran.

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Authors and Affiliations

  1. Department of Chemistry, Yazd Branch, Islamic Azad University, P.O. Box 89195-155, Yazd, Iran

    Alimohammad Dehghan & Sonia Singh

  2. Department of Chemistry, Rafsanjan Vali-e-Asr University, P.O. Box 77176, Rafsanjan, Iran

    Mohammad Anary-Abbasinejad

  3. Department of Chemistry, Zahedan Branch, Islamic Azad University, P.O. Box 98135-978, Zahedan, Iran

    Alireza Hassanabadi

Authors
  1. Alimohammad Dehghan
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  2. Sonia Singh
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  3. Mohammad Anary-Abbasinejad
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  4. Alireza Hassanabadi
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Correspondence to Alimohammad Dehghan.

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Dehghan, A., Singh, S., Anary-Abbasinejad, M. et al. Four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium carbonate. Res Chem Intermed 41, 1001–1009 (2015). https://doi.org/10.1007/s11164-013-1250-9

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  • DOI: https://doi.org/10.1007/s11164-013-1250-9

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