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An efficient and eco-friendly synthesis of quinolinyl chalcones under solvent-free conditions at room temperature

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Abstract

A simple, rapid and eco-friendly procedure for the synthesis of quinolinyl chalcones involving grinding of quinoline-3-carbaldehydes and acetophenones with anhydrous barium hydroxide (C-200) at room temperature under solvent-free conditions has been described. The protocol is much more efficient as the reactions are carried out at room temperature, and yields are also quite high, and the use of hazardous chemicals and organic solvents at any stage of the reaction is also avoided.

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  1. Department of Chemistry, BRCM College of Engineering and Technology, Bahal, 127028, India

    Dinesh Sharma

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  1. Dinesh Sharma
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Sharma, D. An efficient and eco-friendly synthesis of quinolinyl chalcones under solvent-free conditions at room temperature. Res Chem Intermed 41, 927–933 (2015). https://doi.org/10.1007/s11164-013-1245-6

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  • DOI: https://doi.org/10.1007/s11164-013-1245-6

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