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Influence of step-wise aeration treatment on biomass and bioactive compounds of Panax ginseng adventitious root in balloon-type bubble bioreactor

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Abstract

In this study, based on the time profiles of growth and specific oxygen uptake rate in Panax ginseng adventitious root, step-wise aeration treatment was conducted using a 5-L balloon-type bubble bioreactor to enhance root density and metabolite production. The results showed that step-wise aeration of 0.3–0.5–0.3 vvm was found to be optimal for the accumulation of biomass, total saponins content, and polysaccharide content. Such optimization of the aeration volume will be beneficial for the large-scale production of biomass and bioactive compounds of ginseng adventitious root.

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Abbreviations

SOUR:

Specific oxygen uptake rate

BTBB:

Balloon-type bubble bioreactor

2, 4-D:

2, 4-dichlorophenoxyacetic acid

KT:

Kinetin

IBA:

Indole-3-butric acid

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Authors and Affiliations

  1. Tianjin Key Laboratory for Modern Drug Delivery and High Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China

    Juan Wang & Wenyuan Gao

  2. Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin University of Science and Technology, Tianjin, 300457, China

    Qin Wang, Shuli Man & Liming Zhang

Authors
  1. Juan Wang
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  2. Wenyuan Gao
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  3. Qin Wang
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  4. Shuli Man
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  5. Liming Zhang
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Correspondence to Wenyuan Gao.

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Wang, J., Gao, W., Wang, Q. et al. Influence of step-wise aeration treatment on biomass and bioactive compounds of Panax ginseng adventitious root in balloon-type bubble bioreactor. Res Chem Intermed 41, 623–629 (2015). https://doi.org/10.1007/s11164-013-1215-z

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  • DOI: https://doi.org/10.1007/s11164-013-1215-z

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