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Electroreduction of 6-amino-5-nitroso-1,3-dimethyluracil on polycrystalline platinum and nickel cathodes in acid aqueous solution

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Abstract

The reduction of 6-amino-5-nitroso-1,3-dimethyluracil (ANDMU) is a key step in caffeine synthesis. Electroreduction technology is a promising green chemical process. The voltammetric behavior of ANDMU at polycrystalline platinum and nickel cathodes was studied. The Nicholson theory was used to resolve the reduction process semi-quantitatively. The results show that ANDMU mainly undergoes an ECE (electron transfer, chemical reaction, electron transfer) process involving four electrons on the platinum and nickel cathodes in which the two electron-transfer steps occur at almost the same potential and the rate of the coupling chemical reaction between two electron-transfer steps is very fast. Apparent kinetic data and diffusion coefficient were determined for the platinum rotating-disk electrode.

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Acknowledgments

The author acknowledges the National Nature Science Foundation of China (no. 21067002) and Nature Science Foundation of Hainan Province of China (no. 808160) for supporting the study.

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Authors and Affiliations

  1. Department of Pharmacy, Hainan Medical College, Haikou, 571101, China

    Rong Chen

  2. Institute of Nuclear Energy and New Energy Technology, Tsinghua University, Beijing, 100084, China

    Xianglong Zheng & Xien Hu

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  1. Rong Chen
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  2. Xianglong Zheng
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  3. Xien Hu
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Correspondence to Rong Chen.

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Chen, R., Zheng, X. & Hu, X. Electroreduction of 6-amino-5-nitroso-1,3-dimethyluracil on polycrystalline platinum and nickel cathodes in acid aqueous solution. Res Chem Intermed 38, 1119–1132 (2012). https://doi.org/10.1007/s11164-011-0448-y

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  • DOI: https://doi.org/10.1007/s11164-011-0448-y

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