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Early diagnosis and prevention of diabetes in developing countries

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Abstract

Type 2 diabetes has an insidious onset with a long latent period of dysglycaemia. By the time the diagnosis of diabetes is made, diabetes-related tissue damage occurs in nearly half of the patients. Even after diagnosis, the glycaemic control is suboptimal in more than 50%, leading to the vascular complications. Evidences suggest that early detection of diabetes by appropriate screening methods, especially in subjects with high risk for diabetes will help to prevent or delay the vascular complications and thus reduce the clinical, social and economic burden of the disease. There are also evidences to show that intervention at the prediabetic stage is superior to diagnosis of diabetes.

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Abbreviations

DCCT:

Diabetes Control and Complication Trial

UKPDS:

United Kingdom Prospective Diabetes Study

EDIC:

Epidemiology of Diabetes Intervention and Complicaitons

DPP:

Diabetes Prevention Programme

DPS:

Diabetes Prevention Study

IDPP-1:

Indian Diabetes Prevention Programme-1

ADDITION:

Anglo Danish Dutch Study of Intensive Treatment in People with Screen Detected Diabetes in Primary Care

ADA:

American Diabetes Association

IDF:

International Diabetes Federation

WDF:

World Diabetes Foundation

OGTT:

oral glucose tolerance test

IGT:

impaired glucose tolerance

IFG:

impaired fasting glucose

LSM:

life style modification

CVD:

cardiovascular disease

GDM:

gestational diabetes mellitus

NCD:

non-communicable diseases

NDCP:

National Diabetes Control Programmes

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  1. India Diabetes Research Foundation, Dr. A. Ramachandran’s Diabetes Hospitals, 28, Marshall’s Road, Egmore, Chennai-600 008, India

    Ramachandran Ambady & Snehalatha Chamukuttan

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  1. Ramachandran Ambady
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Ambady, R., Chamukuttan, S. Early diagnosis and prevention of diabetes in developing countries. Rev Endocr Metab Disord 9, 193–201 (2008). https://doi.org/10.1007/s11154-008-9079-z

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