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The impact of new screen-detected and previously known type 2 diabetes on health-related quality of life: a population-based study in Qingdao, China

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Abstract

Aims

To examine and compare health-related quality of life (HRQoL) in people with previously known diabetes, new screen-detected asymptomatic diabetes and people without diabetes.

Methods

HRQoL of 4,613 individuals who participated in a population-based cross-sectional diabetes survey in Qingdao, China, in 2009, was assessed using the 15D instrument. A Tobit regression model to estimate the effects of diabetes on HRQoL separate from effects of other health determinants was constructed.

Results

Among the surveyed population, 220 (4.8 %) individuals had previously known diabetes and 531 (11.5 %) individuals had new screen-detected diabetes, defined by fasting plasma glucose ≥7.0 mmol/l and/or 2-h plasma glucose ≥11.1 mmol/l. The age-, gender-, and BMI-adjusted mean 15D score of people without diabetes, with new screen-detected diabetes, and previously known diabetes was 0.975, 0.975, and 0.964, respectively, for urban and 0.971, 0.972, and 0.960, respectively, for rural participants. HRQoL overall and on all the dimensions (p < 0.05) except for hearing, eating, and speech was worse in the people with previously known diabetes compared to those with new screen-detected diabetes and those without diabetes. Compared to people without diabetes, people with new screen-detected diabetes were worse off on the dimension of usual activities (p < 0.05). After adjusting for comorbid diseases and other confounders, the impact of diabetes on reduced HRQoL was diminished.

Conclusion

Health-related quality of life was impaired in people with previously known diabetes who had co-morbid conditions, but was largely unaltered in people with newly detected asymptomatic diabetes as compared to people without diabetes.

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Acknowledgments

The studies were designed and organized by researchers from the University of Helsinki, Helsinki, Finland; Qingdao Municipal Centers for Disease Control and Prevention (CDC), and the Qingdao Endocrinology and Diabetes Hospital and Institute, Qingdao, China. The field investigation of the surveys was supported by the Qingdao Municipal Health Bureau, the Qingdao Municipal Centers for Disease Control and Prevention, and local Health Bureau and CDC in Huangdao, Jiaonan, Shinan, Shibei, Jimo and Sifang districts.

Conflict of interest

Harri Sintonen is the developer of the 15D. The others have nothing to declare.

Author information

Authors and Affiliations

  1. Department of Public Health, Hjelt Institute, University of Helsinki, Mannerheimintie 172, PL41, 00014, Helsinki, Finland

    Yanlei Zhang, Harri Sintonen & Qing Qiao

  2. Qingdao Municipal Centre for Disease Control and Prevention, Qingdao, Shandong, China

    Jianping Sun, Zengchang Pang & Feng Ning

  3. Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China

    Xiaoyong Wang

  4. AstraZeneca, Shanghai, China

    Weiguo Gao

  5. Department of Non-communicable Disease Prevention, Shandong Province Centre for Disease Control and Prevention, Jinan, Shandong, China

    Jie Ren

  6. World Diabetes Foundation, Gentofte, Denmark

    Anil Kapur

  7. R&D, AstraZeneca, Mölndal, Sweden

    Qing Qiao

Authors
  1. Yanlei Zhang
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  2. Jianping Sun
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  3. Zengchang Pang
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  4. Xiaoyong Wang
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  5. Weiguo Gao
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  6. Feng Ning
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  7. Jie Ren
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  8. Anil Kapur
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  9. Harri Sintonen
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  10. Qing Qiao
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Corresponding author

Correspondence to Yanlei Zhang.

Additional information

Yanlei Zhang and Jianping Sun have contributed equally to this work.

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Zhang, Y., Sun, J., Pang, Z. et al. The impact of new screen-detected and previously known type 2 diabetes on health-related quality of life: a population-based study in Qingdao, China. Qual Life Res 23, 2319–2326 (2014). https://doi.org/10.1007/s11136-014-0674-z

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