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Adherence to Antidepressant Therapies in Patients with Depressive Disorders Attending an Outpatient Clinic in a Public Mental Health Hospital, Antioquia, Colombia in 2017

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Abstract

To evaluate the level of adherence to antidepressant therapies and associated factors in patients with depressive disorders. a cross-sectional analytical study was conducted in patients diagnosed with depressive disorders. The sample was for convenience, and a survey including sociodemographic, clinical, and therapeutic variables was designed. The Morisky–Green test, Beliefs about Medicines Questionnaire, and Simplified Medication Adherence Questionnaire were also used, all of which have been validated for assessing adherence in patients with depression. The qualitative variables were evaluated with absolute and relative frequencies, and a bivariate analysis was performed. This study included 54 patients with an average age of 49.5 ± 13.7 years, and 83.3% were women. All patients were diagnosed with major depression, and 9.25% also had an anxiety disorder. According to the Morisky–Green test, only 37% of patients were compliant with the drug therapy, although this was not statistically significant. Women were less compliant than men (33.3% versus 55.6%; p = 0.21). The beliefs that patients have regarding medication do not have a great impact on adherence to antidepressant therapy. However, it was evidenced that adherent patients had less doubts about the medication administered in comparison to non-adherent patients.

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Acknowledgments

We want to thank all the people who made the realization of this project possible.

Funding

This study was funded by Universidad Pontificia Bolivariana, grant number 688B-09/16–55.

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Authors and Affiliations

  1. Escuela de Ciencias de la Salud, Facultad de Medicina, Universidad Pontificia Bolivariana, Calle 78 B N 72 a 109, Medellín, Colombia

    Julio César Restrepo Zapata, Gloria Inés Martínez Dominguez, Lina María Martínez-Sánchez, María de los Ángeles Rodríguez-Gázquez, Juan Ricardo Gaviria García, Andrea Urrego Vásquez, Juan Pablo Ospina-Sánchez, Natalia Morales Quintero, Felipe Hernández Restrepo & Sol Beatriz Ochoa Uribe

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  1. Julio César Restrepo Zapata
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  2. Gloria Inés Martínez Dominguez
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  3. Lina María Martínez-Sánchez
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  4. María de los Ángeles Rodríguez-Gázquez
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  5. Juan Ricardo Gaviria García
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  6. Andrea Urrego Vásquez
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  7. Juan Pablo Ospina-Sánchez
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  8. Natalia Morales Quintero
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  9. Felipe Hernández Restrepo
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  10. Sol Beatriz Ochoa Uribe
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Corresponding author

Correspondence to Lina María Martínez-Sánchez.

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The authors declare no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Zapata, J.C.R., Dominguez, G.I.M., Martínez-Sánchez, L.M. et al. Adherence to Antidepressant Therapies in Patients with Depressive Disorders Attending an Outpatient Clinic in a Public Mental Health Hospital, Antioquia, Colombia in 2017. Psychiatr Q 91, 183–190 (2020). https://doi.org/10.1007/s11126-019-09696-3

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  • DOI: https://doi.org/10.1007/s11126-019-09696-3

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