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Prevalence of anxiety disorder in patients with type 2 diabetes: a nationwide population-based study in Taiwan 2000–2010

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Abstract

This study investigates the prevalence of anxiety disorder (AD) in Taiwanese patients with type 2 diabetes (T2D). Study participants were identified based on at least one service claim for ambulatory or inpatient care with a principal diagnosis of AD and at least 2 service claims for ambulatory care or one service claim for inpatient care with a principal diagnosis of T2D, as listed in the National Health Insurance database of Taiwan. The prevalence of AD decreased from 13.75 to 11.00 % in patients with T2D, whereas it increased from 4.17 to 6.09 % in the general population during the 2000–2010 period. A high prevalence of AD in patients with T2D was associated with age >30 years, the female sex, living in the northern region, comorbidities of congestive heart failure, peripheral vascular disease, cerebrovascular disease, and depression disorder, and a Charlson participant comorbidity index of ≥1. A low prevalence of AD in patients with T2D was associated with residency in urban areas, the comorbidity of hemiplegia or paraplegia, the usage of metformin and sulfonylureas, and rapid-acting insulin injection therapy. The prevalence of AD was higher in patients with T2D than in the general population. Therefore, more public health emphasis is required for preventing and treating AD in patients with T2D, specifically those with the mentioned risk factors.

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Acknowledgments

This study is based in part on data from the National Health Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health and managed by National Health Research Institutes (NHIRD-100-100 and NHIRD-102-135). The interpretation and conclusions contained herein do not represent those of the aforementioned agencies. This study was supported by Grants from Kaohsiung Medical University Hospital (KMUH99-9M26), Kaohsiung Municipal Ta-Tung Hospital (kmtth-100-010 and kmtth-101-013), and Ministry of Science and Technology (MOST 104-2314-B-037-036).

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Authors and Affiliations

  1. Department of Public Health and Environmental Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

    Hung-Pin Tu

  2. Department of Adult Psychiatry, Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan

    Ching-Hua Lin

  3. Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, 100, Shih-Chuan 1st Road, San Ming District, Kaohsiung, 807, Taiwan

    Ching-Hua Lin, Peng-Wei Wang & Chun-Jen Huang

  4. Department of Public Health, Kaohsiung Medical University, Kaohsiung, Taiwan

    Hui-Min Hsieh

  5. Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

    He-Jiun Jiang

  6. Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

    Peng-Wei Wang & Chun-Jen Huang

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  1. Hung-Pin Tu
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Correspondence to Chun-Jen Huang.

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This study is within the scope of exemption categories for Institutional Review Board (IRB) review certified by Kaohsiung Medical University IRB, Taiwan.

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Tu, HP., Lin, CH., Hsieh, HM. et al. Prevalence of anxiety disorder in patients with type 2 diabetes: a nationwide population-based study in Taiwan 2000–2010. Psychiatr Q 88, 75–91 (2017). https://doi.org/10.1007/s11126-016-9436-0

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  • DOI: https://doi.org/10.1007/s11126-016-9436-0

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