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Artemisia argyi H. Lév. & Vaniot: a comprehensive review on traditional uses, phytochemistry, and pharmacological activities

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Abstract

Artemisia argyi, a perennial herb of the genus Artemisia, is recorded as medicine for the treatment of various diseases, such as metrorrhagia, menorrhagia, irregular menstruation, hemorrhage, dysmenorrhea, eczema and skinitch. The dried leaves of A. argyi can be made into moxa floss, which is the raw material of moxibustion. In addition, A. argyi is also one of the symbols of the Dragon Boat Festival in China and its shoots and seedlings can be used as tea and vegetables. Therefore, A. argyi has attracted extensive attentions due to its various chemical constituents and biological activities, as well as its extensive clinical and folk applications. Phytochemical investigation of A. argyi has led to the isolation of sesquiterpenoids, flavonoids, triterpeniods, volatile oils, and others, especially sesquiterpenoids, which are the most characteristic components. The crude extracts and the isolated compounds from A. argyi reveal diverse biological activities, including antibacterial, anti-tumor, anti-inflammatory, antioxidant, etc. Although most biological activities are only the results of in vitro experiments. The aim of this review is to provide a summary on the traditional efficacy, folk application, phytochemistry and modern pharmacological research of A. argyi, which will bring more attention to other researchers for further study.

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Acknowledgements

This research was funded by Henan Provincial High-Level Talents International Training Funding Project (2021-72) and Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources (2060302).

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Authors and Affiliations

  1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China

    Wen-Jun Wei, Tao Guo, Gui-Min Xue & Rui Ma

  2. Henan Engineering Research Center of Medicinal and Edible Chinese Medicine Technology, Zhengzhou, 450046, China

    Wen-Jun Wei & Tao Guo

  3. State Key Laboratory of Component-Based Chinese Medicine, Tianjin Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China

    Yuefei Wang

  4. College of Pharmacy and Health Sciences, St John’s University, New York, USA

    Zhe-Sheng Chen

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WJW contributed to data collection, manuscript preparation, revision, concepts, and design; YW made revision; GMX provided data information; TG and RM offered fund support. WJW, TG, YW, and ZSC discussed and approved the final version.

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Correspondence to Tao Guo, Yuefei Wang or Zhe-Sheng Chen.

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Wei, WJ., Guo, T., Xue, GM. et al. Artemisia argyi H. Lév. & Vaniot: a comprehensive review on traditional uses, phytochemistry, and pharmacological activities. Phytochem Rev (2024). https://doi.org/10.1007/s11101-023-09910-y

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