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Camellia nitidissima C.W. Chi: a review of botany, chemistry, and pharmacology

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Abstract

Camellia nitidissima C.W. Chi, honored as “the Queen of Camellia”, has attracted considerable attention as a rare and famous ornamental species characterized by yellow waxy petals. Its flowers and leaves have been used in Chinese folk herbal medicine to treat dysentery, hypertension, diarrhea, faucitis, hepatitis with jaundice, liver cirrhosis, sores, malignant tumors, and irregular menstruation. In recent years, a great number of phytochemical, pharmacological, and toxicity studies on C. nitidissima have been carried out, primarily in China. Phytochemical investigations have shown that the plant contains a rich source of bioactive constituents, including flavonoids, polysaccharides, saponins, volatile compounds, and other components such as mineral elements and amino acids. Both in vitro and in vivo pharmacological studies have demonstrated that C. nitidissima possesses anticancer, antioxidant, hypolipidemic, hypoglycemic, antiallergic, immunomodulatory, antibacterial, anxiolytic, and antidepressant properties. The present paper presents an up-to-date and comprehensive overview of the botany, processing, chemical constituents, pharmacological effects, and toxicity of C. nitidissima in order to provide scientific credence for this traditional medicine while exploring the potential of this plant for drug development.

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Acknowledgements

This work was supported by the National Public Science and Technology Research Funds Projects of Ocean (201405003) and the Cultivation Plan for Youth Agricultural Science and Technology Innovative Talents of Liaoning Province (2014007). This work was partly supported by the Agriculture Science Technology Achievement Transformation Fund (2013GB2B020531).

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Authors and Affiliations

  1. School of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Ganjingzi District, Dalian, 116024, People’s Republic of China

    Dongye He, Xiaoyu Li, Xuan Sai, Lili Wang & Yongping Xu

  2. Ministry of Education Center for Food Safety of Animal Origin, Dalian University of Technology, Dalian, 116620, China

    Dongye He, Xiaoyu Li, Xuan Sai, Lili Wang & Yongping Xu

  3. Dalian SEM Bio-Engineering Technology Co. Ltd., Dalian, 116620, China

    Shuying Li & Yongping Xu

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  1. Dongye He
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  2. Xiaoyu Li
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  3. Xuan Sai
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  4. Lili Wang
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  5. Shuying Li
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Correspondence to Yongping Xu.

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He, D., Li, X., Sai, X. et al. Camellia nitidissima C.W. Chi: a review of botany, chemistry, and pharmacology. Phytochem Rev 17, 327–349 (2018). https://doi.org/10.1007/s11101-017-9537-x

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  • DOI: https://doi.org/10.1007/s11101-017-9537-x

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