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This article was updated to correct Figs. 1 and 4 as author corrections were overlooked during the production process.
Schematic diagram of methods of MAP estimation used in the study. Standard MAP executes estimation once using all historical TDM data (a); Adaptive MAP executes estimation iteratively using each segment of historical TDM data with updated prior mean by posterior mode from its preceding iteration and repeats until the last iteration, i.e. 0 to m1, …, mn-1 to mn (b). Weighted MAP executes estimation once using all historical TDM data with weighted importance (likelihood) of each segment of data during the estimation (c).
The percentage error of Bayesian forecasting using the weighted MAP method for all combinations of weighting factors ΔTRef and α. ΔTRef and α are both weighting factors. ΔTRef is the reference day, defined as the cutoff value of the time distance where w(Ys) is 1, i.e.where ΔTRef equals ΔT Ys . α is the unitless effect size of the weighting function w(Ys) on the likelihood f(η| Y).
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Guo, T., van Hest, R.M., Zwep, L.B. et al. Correction to: Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients. Pharm Res 37, 223 (2020). https://doi.org/10.1007/s11095-020-02934-5
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DOI: https://doi.org/10.1007/s11095-020-02934-5