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Current Trends in the Development of Technologies for Matrix Formulations with Modified Release (Review)

  • DRUG SYNTHESIS METHODS AND MANUFACTURING TECHNOLOGY
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Pharmaceutical Chemistry Journal Aims and scope

Current aspects of the technology used to create matrix formulations ar presented. The main types of matrix are described depending on their behavior in the body; matrix-forming ingredients available on the Russian market are reviewed and the main principles determining their selection are discussed, along with the main technological principles underlying the preparation of matrix formulations. Technical factors affecting release of active substances from matrixes are addressed. Experimental data on release from matrix tablets based on composite polymer carriers are presented.

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Authors and Affiliations

  1. I. M. Sechenov First Moscow Medical University, Russian Ministry of Health, 8 Trubetskaya Street, 119991, Moscow, Russia

    N. B. Demina

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  1. N. B. Demina
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Correspondence to N. B. Demina.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 7, pp. 44 – 50, July, 2016.

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Demina, N.B. Current Trends in the Development of Technologies for Matrix Formulations with Modified Release (Review). Pharm Chem J 50, 475–480 (2016). https://doi.org/10.1007/s11094-016-1472-4

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  • DOI: https://doi.org/10.1007/s11094-016-1472-4

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