A relationship between the composition of essential oils and their ability to inhibit the model reaction of cumene radical oxidation was established. It was shown that azulene-containing essential oils of chamomile, yarrow, and wormwood were capable of inhibiting the model reaction of initiated cumene oxidation, which was indicative of antioxidant activity. It was shown that the greater the content of chamazulene was, the higher the antioxidant activity of the essential oil was. Essential oil of yarrow had a high chamazulene content (26%) and the maximum antiradical activity of the studied samples.
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Acknowledgments
We thank I. G. Vshivkov for supplying samples of yarrow, wormwood, and fir essential oils; staff of Silvestris & Szilas Ltd., Hungary, samples of chamomile and yarrow essential oils. We thank Dr. A. V. Tkachev (IOC, Novosibirsk) for providing GC—MS analysis of the essential oils.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 6, pp. 42 – 44, June, 2012.
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Sizova, N.V. Composition and antioxidant activity of essential oils containing azulene derivatives. Pharm Chem J 46, 369–371 (2012). https://doi.org/10.1007/s11094-012-0800-6
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DOI: https://doi.org/10.1007/s11094-012-0800-6