A series of 5-aryl-4-acyl(heteroyl)-3-hydroxy-1-(3-ethoxypropyl)-3-pyrrolin-2-ones were synthesized using the reaction of 3-ethoxypropylamine with a mixture of aromatic aldehyde and methyl esters of acyl(heteroyl)- pyruvic acid. The antimicrobial activity of the synthesized compounds was studied.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 1, pp. 26 – 28, January, 2012.
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Gein, V.L., Bobyleva, A.A., Levandovskaya, E.B. et al. Synthesis and antimicrobial activity of 5-aryl-4-acyl(heteroyl)-3-hydroxy-1- (3-ethoxypropyl)-3-pyrrolin-2-ones. Pharm Chem J 46, 23–25 (2012). https://doi.org/10.1007/s11094-012-0728-x
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DOI: https://doi.org/10.1007/s11094-012-0728-x