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Experience in creating new drugs using traditional technologies

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Pharmaceutical Chemistry Journal Aims and scope

Working hypotheses for the creation of new potential drugs including Class III antiarrhythmic (nibentan, niferidyl), antiallergic (theoritin), and antituberculosis (hixozid) agents are formulated and experimental data on the activity of the obtained compounds are presented.

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References

  1. R. G. Glushkov, S. P. Golitsyn, E. V. Dorodnikova, et al., Vestn. Ross. Akad. Med. Nauk, No. 11, 38–42 (1998).

  2. R. G. Glushkov, M. D. Mashkovski, and S. D. Yuzhakov, Drugs Future, 22, 30–33 (1997).

    CAS  Google Scholar 

  3. R. G. Glushkov, S. D. Yuzhakov, A. I. L?vov, et al., Khim.-farm. Zh., 45(2), 3–12 (2011).

    Google Scholar 

  4. R. G. Glushkov and A. I. L’vov, RF Pat. No. 2059612, “Method for preparing 1-phenyl-(1-p-nitrobenzoylamino)-5-N,N-diethylaminopentane and 1-phenyl-1-amino-5-N,N-diethylaminopentane hydrochloride”; Byull. Izobret., No. 13 (1996).

  5. M. D. Mashkovski, R. G. Glushkov, S. Ya. Skachilova, et al., SU Pat. No. 1833612, “1-Phenyl-1-(p-nitrobenzoylamino)-5-N-piperidino)- or (N,N-diethylamino)pentane hydrochlorides exhibiting anti-arrhythmic and antifibrillatory activity” (1987).

  6. M. D. Mashkovski, R. G. Glushkov, E. V. Dorodnikova, et al., Khim.-farm. Zh., 29(3), 27–31 (1995).

    Google Scholar 

  7. L. V. Rozenshtraukh and E. P. Anyukhovskii, Kardiologiya, 35(5), 25–36 (1995).

    Google Scholar 

  8. E. B. Maikov, S. A. Bakalov, I. B. Krutanov, et al., Kardiologiya, 36(6), 38–51 (1996).

    Google Scholar 

  9. M. Ya. Ruda, I. N. Merkulova, A. E. Tararak, et al., Kardiologiya, 36(6), 28–37 (1996).

    Google Scholar 

  10. E. B. Maikov, S. A. Bakalov, I. B. Krutanov, et al., Kardiologiya, 35(5), 10–18 (1995).

    Google Scholar 

  11. R. G. Glushkov and S. D. Yuzhakov, Khim.-farm. Zh., 45(1), 3–13 (2011).

    Google Scholar 

  12. R. G. Glushkov and S. D. Yuzhakov, RF Pat. No. 2,333,212, “Derivatives of 1- and 7-[omega-(benzhydryl-4-piperazinyl-1)alkyl]xanthines exhibiting antihistamine and anti-allergic activity”; Byull. Izobret., No. 25 (2008).

  13. M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2005), p. 292.

    Google Scholar 

  14. R. G. Glushkov, M. I. Perel’man, G. B. Sokolova, et al., RF Pat. No. 2209067, “Combined antituberculosis drugs as a composite of quinoxalin-1,4-dioxide derivatives with known antituberculosis drugs”; Byull. Izobret., No. 21 (2003).

  15. R. G. Glushkov, G. B. Sokolova, L. Yu. Krylova, et al., Probl. Tuberk. Bolezn. Legk., No. 3, 20–25 (2007).

  16. R. G. Glushkov and G. B. Sokolova, Antibiot. Khimioter., 53(5–6), 11–13 (2008).

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Mirfarm Company, Obninsk, Kaluga Oblast, Russia

    R. G. Glushkov & S. D. Yuzhakov*

Authors
  1. R. G. Glushkov
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  2. S. D. Yuzhakov*
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* S. D. Yuzhakov, deceased.

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 9, pp. 3–7, September, 2011.

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Glushkov, R.G., Yuzhakov*, S.D. Experience in creating new drugs using traditional technologies. Pharm Chem J 45, 517–521 (2011). https://doi.org/10.1007/s11094-011-0670-3

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  • DOI: https://doi.org/10.1007/s11094-011-0670-3

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