Methods for the synthesis of 6,6-substituted 1-aminopyrazolo[3,4-b]pyridines with fused tetrahydropyran (-thiopyran) and pyridine rings have been developed on the basis of condensed 2-chloropyridine derivatives. The coronary vasodilating activity of the synthesized compounds has been studied.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 12, pp. 11–12, December, 2008.
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Dabaeva, V.V., Pilosyan, S.G., Noravyan, A.S. et al. Synthesis and coronary vasodilating activity of 1-aminopyrazolo[3,4-b]pyridines with fused tetrahydropyran (-thiopyran) and piperidine rings. Pharm Chem J 42, 668–669 (2008). https://doi.org/10.1007/s11094-009-0218-y
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DOI: https://doi.org/10.1007/s11094-009-0218-y