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Photo-oxidative destruction of hemoglobin in aqueous solutions using high-intensity pulsed continuous-spectrum radiation

  • Drug Synthesis Methods and Manufacturing Technology
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Pharmaceutical Chemistry Journal Aims and scope

A new oxidative process for the destruction of organic proteinaceous compounds in aqueous solutions, based on the combined use of high-intensity pulsed continuous-spectrum radiation and hydrogen peroxide, is proposed and tested experimentally. The radiation source was a high-power pulsed xenon lamp. Studies using an aqueous hemoglobin solution as an example demonstrated the efficient photo-oxidative destruction of a protein, accompanied by significant decreases in chemical oxygen consumption and dry residue. This process might be used in the development of new techniques for cleansing effluents from contemporary industrial drugs and biochemicals production facilities.

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References

  1. A. S. Kamrukov, N. P. Kozlov, A. F. Seliverstov, et al., Safety in the Technosphere [in Russian], No. 1, 38–44 (2006).

  2. I. S. Marshak, Pulsed Light Sources [in Russian], Énergiya, Moscow (1978).

    Google Scholar 

  3. V. P. Arkhipov, A. S. Kamrukov, N. P. Kozlov, et al., Konversiya, No. 6, 46–50 (1996).

  4. R. Marry, D. Grenner, P. Meies, et al., Human Biochemistry [Russian translation] Mir, Moscow (1993).

    Google Scholar 

  5. O. Legrini, E. Oliveros, and A. M. Braun, Chem. Rev., 93, 671–698 (1993).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. OOO “Medbiofarm”, Obninsk, Moscow Region, Russia

    A. Ya. Goncharova & N. N. Kutina

  2. N. É. Bauman Science Research Institute of Electromechanics, Moscow State Technical University, Moscow, Russia

    A. S. Kamrukov & N. P. Kozlov

  3. ZAO “Éliks”, Obolensk, Moscow Region, Russia

    A. B. Kirpichenkov

  4. OOO “Gelenpol”, Obninsk, Moscow Region, Russia

    V. A. Sarychev

  5. Institute of Physical Chemistry, Russian Academy of Sciences, Moscow, Russia

    A. F. Seliverstov

Authors
  1. A. Ya. Goncharova
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  2. A. S. Kamrukov
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  3. A. B. Kirpichenkov
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  4. N. P. Kozlov
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  5. N. N. Kutina
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  6. V. A. Sarychev
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  7. A. F. Seliverstov
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 10, pp. 46–48, October, 2008.

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Goncharova, A.Y., Kamrukov, A.S., Kirpichenkov, A.B. et al. Photo-oxidative destruction of hemoglobin in aqueous solutions using high-intensity pulsed continuous-spectrum radiation. Pharm Chem J 42, 596–598 (2008). https://doi.org/10.1007/s11094-009-0178-2

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  • DOI: https://doi.org/10.1007/s11094-009-0178-2

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