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Sensitivity enhancement of SPR sensor assisted by Ag, TiO2 and BP for glucose and hemoglobin detection: numerical analysis

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Abstract

This work aims to investigate the problem glucose and hemoglobin detection in blood samples and other liquids, by using a novel SPR sensors. Our designs is based on Kretschmann configuration, incorporating multi-layers of silver (Ag), titanium dioxide (TiO2), black phosphorus (BP) and gold (Au). Simulations based on transfer matrix method were carried out to compute reflectance of each device. The Impact of Ag, BP and TiO2 on the sensitivity performance are demonstrated. The maximum sensitivity attained is 682.34 deg/RIU with other performance parameters computed, minimum reflection (Rmin) of \(0.14 \%\), detection accuracy of 0.290 deg−1, and quality factor of 171.698 RIU−1. Our proposed devices are expected to plays an active role for recognizing biological or chemical entities in liquids. Numerical results obtained in this paper exhibited high sensitivity in comparison with previously reported studies.

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Acknowledgements

The authors are thankful to Dr. Amit Kumar Goyal for useful comments.

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All authors contributed to the study conception and design. Data collection, investigation, and analysis were performed by IMED SASSI. The first draft of the manuscript was written by IMED SASSI and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Imed Sassi.

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Not applicable. The work presented in this manuscript is mathematical modeling only for the proposed biosensor. No experiment was performed on the human body and living organism/animal. So, ethical approval from an ethical committee is not required.

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Sassi, I., Ben El Hadj Rhouma, M. Sensitivity enhancement of SPR sensor assisted by Ag, TiO2 and BP for glucose and hemoglobin detection: numerical analysis. Opt Quant Electron 55, 959 (2023). https://doi.org/10.1007/s11082-023-05217-6

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  • DOI: https://doi.org/10.1007/s11082-023-05217-6

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