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Gold nanoparticles and graphene oxide based low cost glucose sensing technique

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Abstract

Diabetes is a chronic metabolic disease characterized by abnormally high blood glucose (or blood sugar) levels. Over time, diabetes can cause serious damage to the heart, blood vessels, eyes, kidneys, and nerves. As a result, this work proposes a low-cost glucose sensing method based on graphene oxide (GO) and gold nanoparticles (AuNPs). GO is synthesized from laboratory-grade graphite powder and is used to enhance glucose solution detection via gold nanoparticles (AuNPs). A modified Hummer's method is used to prepare GO, and the Turkevich method is used to synthesize AuNPs in this process. X-ray diffraction (XRD) is used to analyze the structure, whereas Fourier transform infrared spectroscopy (FTIR) is used to study the functional groups attached to the GO. We also used transmission electron microscopy (HR-TEM) to characterize the morphology of GO and AuNPs. A UV–visible spectrophotometer is used to obtain the absorption spectra of synthesized samples. The surface plasmon peak indicates that the sensor has a linear range of glucose concentrations ranging from 1 to 9 mM. With the addition of GO, the sensing performance has been improved.

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Funding

This work is financially supported by the project title “Development of LSPR based optical fiber sensors for bio-medical applications” funded by DIT University, Dehradun, India, with sanction number: [DITU/Dean R&C/2022/003]. S. Kumar acknowledges Double-Hundred Talent Plan of Shandong Province, China.

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Authors and Affiliations

  1. Department of Chemistry, DIT University, Dehradun, Uttarakhand, 248009, India

    Richa Pandey & Naveen Singhal

  2. Materials and Nano Engineering Research Lab, Department of Physics, DIT University, Dehradun, Uttarakhand, 248009, India

    Richa Pandey & Parveen Kumar

  3. Nanophotonics and Plasmonic Biosensor Research Laboratory (NPBRL), Department of Electrical and Electronics and Communication Engineering, DIT University, Dehradun, Uttarakhand, 248009, India

    Kuldeep Choudhary

  4. Shandong Key Laboratory of Optical Communication Science and Technology, School of Physics Science and Information Technology, Liaocheng University, Liaocheng, 252059, Shandong, China

    Santosh Kumar

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  1. Richa Pandey
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  2. Naveen Singhal
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  3. Parveen Kumar
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  4. Kuldeep Choudhary
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  5. Santosh Kumar
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Correspondence to Naveen Singhal.

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Pandey, R., Singhal, N., Kumar, P. et al. Gold nanoparticles and graphene oxide based low cost glucose sensing technique. Opt Quant Electron 54, 448 (2022). https://doi.org/10.1007/s11082-022-03844-z

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  • DOI: https://doi.org/10.1007/s11082-022-03844-z

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