Abstract
The central nucleus of the amygdala (Ce) is a terminal area of the major nociceptive ascending pathway, the spino-(trigemino)-parabrachio-amygdaloid tract. In our study, the Ce was bilaterally electrolytically lesioned in male albino rats. Nociception was assessed by the tail flick latency, which was later compared with the corresponding values in intact and sham-lesioned rats. Stereotactic electrolytic bilateral lesioning of the Ce significantly decreased the sensitivity to pain. In addition, the diurnal variation in the pain sensitivity observed in control animals was noticeably smoothed.
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Neirofiziologiya/Neurophysiology, Vol. 38, No. 3, pp. 231–234, May–June, 2006.
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Balasubramanian, C., Krushna Pal, G. & Konar, D.B. Effect of stereotactic ablation of the central nucleus of the amygdala on pain sensitivity among rats. Neurophysiology 38, 193–196 (2006). https://doi.org/10.1007/s11062-006-0045-7
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DOI: https://doi.org/10.1007/s11062-006-0045-7