Abstract
We present the rare case of a 31-year-old man who developed a germinoma 22 years after resection of a mature teratoma of the pineal region. The initial stereotactic biopsy showed a granulomatous inflammation, but no malignant cells. The correct diagnosis could only be confirmed in a second cerebral biopsy, allowing for proper treatment with radiation therapy. The need to consider metachronous germinoma in this setting is discussed.
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11060_2008_9554_MOESM1_ESM.pdf
Suppl. Fig. 1: Coronar sections of a T1-weighted Magnetic Resonance Imaging: (a) No pathological contrast enhancement can be seen in January 2006 (white arrowhead). (b) Pathological contrast enhancement of the ependymal layer along the ventricles in April 2006 (white arrowhead). (PDF 39 kb)
11060_2008_9554_MOESM2_ESM.pdf
Suppl. Fig. 2: Sagittal sections of a T1-weighted Magnetic Resonance Imaging: No pathological contrast enhancement is noted in the follow-up MRI (white arrowhead). (PDF 394 kb)
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Janzarik, W.G., Müller, K., Lübbert, M. et al. Occurrence of a germinoma 22 years after resection of a mature cerebral teratoma. J Neurooncol 88, 217–219 (2008). https://doi.org/10.1007/s11060-008-9554-0
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DOI: https://doi.org/10.1007/s11060-008-9554-0