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Results of Pharmacotherapy of Attention Deficit Hyperactivity Disorder: Assessment Using Neuropsychological Methods

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Study aim. To investigate the dynamics of measures of behavior, attention, and memory during treatment with Noofen (250-mg capsules) in children with attention deficit hyperactivity disorder (ADHD). Materials and methods. A total of 50 patients taking part in an open study were divided into two groups of 25 patients: patients of group 1 received Noofen while patients of group 2 (controls) received only low doses of multivitamins. Treatment lasted one month. Noofen was given at doses of 15–20 mg/kg (500–750 mg) per day using 250-mg capsules, as two or three doses. Results and conclusions. Neuropsychological test results at the end of one month of treatment demonstrated improvements in cognitive functions, including measures of self-control, sustained, focused, and distributed attention, and auditory verbal memory. It is suggested that the initial positive changes may provide a base for attaining more significant clinical outcomes with longer-lasting treatment.

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Authors and Affiliations

  1. Department of Neurology, Neurosurgery, and Medical Genetics, Faculty of Pediatrics, Pirogov Russian National Medical Research University, Moscow, Russia

    N. N. Zavadenko & N. Yu. Suvorinova

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  1. N. N. Zavadenko
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  2. N. Yu. Suvorinova
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Correspondence to N. N. Zavadenko.

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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 114, No. 9, Iss I, pp. 19–24, September, 2014.

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Zavadenko, N.N., Suvorinova, N.Y. Results of Pharmacotherapy of Attention Deficit Hyperactivity Disorder: Assessment Using Neuropsychological Methods. Neurosci Behav Physi 46, 354–359 (2016). https://doi.org/10.1007/s11055-016-0241-x

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