Abstract
Deep-seated subcutaneous ulcers infected with Candida species are rare. We are reporting a 51-year-old Cantonese woman who had a large, deep-seated subcutaneous ulcer on her right shoulder for more than a year. Direct smears of the purulent extrusion revealed many pseudohyphae and yeast cells. Candida species were isolated from the purulent extrusion and further identified as Candida albicans and C. parapsilosis. A skin lesion biopsy contained yeast cells and pseudohyphae. C. parapsilosis were once isolated from the biopsy specimen. Total healing was obtained with itraconazole (200 mg twice daily for 16 days and then 100 mg twice daily for 14 days) combined with phototherapy.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ginter G, Rieger E, Soyer HP, Hoedl S. Granulomatous panniculitis caused by Candida albicans: a case presenting with multiple leg ulcers. J Am Acad Dermatol 1993;28:315–7.
Galimberti RL, Flores V, Gonzalez Ramos MC, Villaba LI. Cutaneous ulcers due to Candida albicans in an immunocompromised patient-response to therapy with itraconazole. Clin Exp Dermatol 1989;14:295–7.
Tomecki KJ, Dijkstra JW, Hall GS, Steck WD. Systemic mycoses. J Am Acad Dermatol 1989;21:1285–93.
Bartie KL, Williams DW, Wilson MJ, Potts AJ, Lewis MA. Differential invasion of Candida albicans isolates in an in vitro model of oral candidosis. Oral Microbiol Immunol 2004;19:293–6.
Jayatilake JA, Samaranayake YH, Cheung LK, Samaranayake LP. Quantitative evaluation of tissue invasion by wild type, hyphal and SAP mutants of Candida albicans, and non-albicans Candida species in reconstituted human oral epithelium. J Oral Pathol Med 2006;35:484–91.
Patterson JW, Brown PC, Broecker AH. Infection-induced panniculitis. J Cutan Pathol 1989;16:183–93. .
Pinheiro AL, Meireles GC, de Barros Vieira AL, Almeida D, Carvalho CM, dos Santos JN. Phototherapy improves healing of cutaneous wounds in nourished and undernourished Wistar rats. Braz Dent J 2004;15:SI21–28.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Xi, L., Li, X., Zhang, J. et al. Good response in a patient with deep-seated subcutaneous ulcer due to Candida species. Mycopathologia 164, 77–80 (2007). https://doi.org/10.1007/s11046-007-9030-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11046-007-9030-y