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Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China

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Abstract

In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.

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Acknowledgments

This project supported by the National Natural Science Foundation of China (Nos. 30700470 and 30871348), and the Shaan’xi Provincial Science and Technology Research and Development Project Fund (No. 2008K09-02), China. We would like to thank all donors for making this work possible, Dr. Natalia Bogatcheva for the nice suggestions and Dr. Zhivotovsky for the kind helps with the figures in this manuscript.

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Correspondence to Zhen-min Lian.

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The first two authors equally contributed to this work.

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Zhu, Bf., Yang, G., Shen, Cm. et al. Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China. Mol Biol Rep 37, 3889–3895 (2010). https://doi.org/10.1007/s11033-010-0045-y

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