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MgCl2 and its applications in organic chemistry and biochemistry: a review

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Abstract

MgCl2 has been reported to be a versatile reagent especially as a Lewis acid catalyst in a variety of organic transformations including the preparation of heterocyclic compounds, the protection of functional groups and condensation reaction. Also the use of MgCl2 in the preparation of metallic magnesium and the application of magnesium chloride in biochemistry such as anesthetic for cephalopods, the separation of serum high-density lipoprotein, effect of MgCl2 on rabbit bronchial smooth muscle, antimicrobial properties of magnesium chloride and effect of MgCl2 on the quality of life for patients with fibromyalgia have been reported. Therefore, in this article the use of MgCl2 in organic chemistry and biochemistry is reviewed.

Graphical abstract

MgCl2 has been reported to be a versatile reagent especially as a Lewis acid catalyst in a variety of organic transformations including the preparation of heterocyclic compounds, the protection of functional groups and condensation reaction. Also the use of MgCl2 in the preparation of metallic magnesium and the application of magnesium chloride in biochemistry such as anesthetic for cephalopods, the separation of serum high-density lipoprotein, effect of MgCl2 on rabbit bronchial smooth muscle, antimicrobial properties of magnesium chloride and effect of MgCl2 on the quality of life for patients with fibromyalgia have been reported. Therefore, in this article the use of MgCl2 in organic chemistry and biochemistry is reviewed.

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  1. Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran

    Toktam Shiebani Daloee & Farahnaz K. Behbahani

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Correspondence to Farahnaz K. Behbahani.

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Daloee, T.S., Behbahani, F.K. MgCl2 and its applications in organic chemistry and biochemistry: a review. Mol Divers 24, 463–476 (2020). https://doi.org/10.1007/s11030-019-09947-2

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