Skip to main content
Log in

Clinical and Operational Risk: A Bayesian Approach

  • Published:
Methodology and Computing in Applied Probability Aims and scope Submit manuscript

Abstract

In health care organizations (HCOs) adverse events may provoke dangerous consequences on patients, such as death, a longer hospital stay, and morbidity. As a consequence, HCO’s department needs to manage legal issues and economic reimbursements. Governances and physicians are interested in operational (OR) and clinical risk (CR) assessment, mainly for forecasting and managing losses and for a correct decision making. Currently, scientific researches, which are objected to a quantification of CR and OR in HCO, are scarce; absence of regulatory constraints and limited awareness of benefits due to risk management do not provide incentives to elaborate on how risks can be quantified. This paper is aimed at proposing Bayesian methods to manage operational and clinical adverse events in health care. Bayesian Networks (BNs) are useful for assessing risks given end stage renal disease (ESRD) as a context of application; some prior probability distributions are advised for representing knowledge before experimental results and Bayesian utility functions for making the optimal decision. The method is described as from the theoretical as from the empirical point of view, thanks to the health care and haemodialysis department, for this application. The ultimate goal is to introduce a methodology useful for managing operational and clinical risk for haemodialysis patients and departments.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • J. M. Bernardo, and A. F. M. Smith, Bayesian Theory, John Wiley and Sons: New York, 1994.

    MATH  Google Scholar 

  • G. F. Cooper, and E. Herskovits, “A Bayesian method for the induction of probabilistic networks from data,” Machine Learning vol. 9 no. 4 pp. 309–347, Oct. 1992.

  • C. Cornalba, Risk Management Models in Health Care: Methods and Applications for the Assessment of Clinical and Operational Risk, University of Pavia, PhD Dissertation, 2006.

  • DOQI Group, “K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease,” American Journal of Kidney Disease vol. 42 no. 3 pp. 1–201, 2003.

  • ESRD Group, ESRD Glossary, Medicare ESRD Network Organizations, 2006.

  • FDA Administration, Guidance for the Use of Bayesian Statistics in Medical Device Clinical Trials. Technical report, Food and Drug Administration, Center for Devices and Radiological Health, Division of Biostatistics, 2006.

  • A. Frachot, O. Moudoulaud, T. Roncalli, Loss Distribution Approach in Practice. Technical report, Groupe de Recherche Opèrationnelle, Crèdit Lyonnais, France, 2003.

  • T. B. Fomby, and R. Carter Hill, Applying Maximum Entropy to Econometric Problems, JAI Press, 1997.

  • W. T. Grandy, and L. H. Schick, Maximum Entropy and Bayesian Methods. Kluwer, Academic Publishers: Dordrecht, 1999.

    Google Scholar 

  • Institute IOM, “To err is human. Building a safer health system.” In L. Kohn, J. Corrigan, and M. Donaldson (eds.), National Academy Press: Washington, Second edition, 1999.

  • P. D. Grunwald, and A. P. Dawid, “Game theory, maximum entropy, minimum discrepancy, and robust Bayesian decision theory,” Annals of Statistics vol. 32 pp. 1367–1433, 2004.

  • D. J. Hand, H. Mannila, P. Smyth, Principles of Data Mining (Adaptive Computation and Machine Learning), The MIT Press, 2001.

  • E. T. Jaynes, Probability Theory: The Logic of Science. In L. Bretthorst (ed.), Cambridge University Press, 2003.

  • F. V. Jensen, Bayesian Networks and Decision Graphs, Springer, First edition, 2001.

  • J. Kim, R. L. Pisoni, M. Danese, S. Satayathum, P. Klassen, and E. W. Young, “Achievement of proposed NKF-K/DOQI bone metabolism and disease guidelines: results from the dialysis outcomes and practice patterns study (DOPPS),” Journal of the American Society of Nephrology vol. 14 no. 25 pp. 269–270, 2003.

    Google Scholar 

  • H. Kumamoto and E. J. Henley, Probabilistic Risk Assessment and Management for Engineers and Scientist, IEEE Press, Second edition, 1996.

  • R. C. Lee and W. E. Wright, “Development of human exposure-factor distributions using maximum-entropy inference,” Journal of Exposure Analysis and Environmental Epidemiology vol. 4 pp. 329–341, 1994.

    Google Scholar 

  • L. Lorton, Risk Assessment and Management Guide for the Medical Practice, AMA Press, American Medical Association, 2005.

  • J. Pearl, Aspects of Graphical Models Connected with Causality. Proceedings of 49th Session, International Statistical Institute: Invited papers, Florence, Italy, 1993.

  • H. Raiffa, Decision Analysis: Introductory Readings on Choices Under Uncertainty, McGraw Hill, 1997.

  • J. Shao, Mathematical Statistics, Springer, Second edition, 2003.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chiara Cornalba.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cornalba, C. Clinical and Operational Risk: A Bayesian Approach. Methodol Comput Appl Probab 11, 47–63 (2009). https://doi.org/10.1007/s11009-007-9068-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11009-007-9068-9

Keywords

AMS 2000 Subject Classification

Navigation