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Synthesis, characterization and in vitro antimicrobial prospecting of silver-doped ceria

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Abstract

In this work, Ag-doped CeO2 samples containing 0.5 mol% Ag+ were successfully synthesized by the polymeric precursor method and then calcined at 400, 500, 600 and 700 °C for 2 h. X-ray diffraction and Raman spectra indicated that the crystals have a fluorite-type structure without the presence of other phases. The size of the Ce0.95Ag0.05O1.9−δ crystals increased from 6.61 to 27.46 nm upon increasing the thermal treatment temperature. The decomposition of the samples was examined by differential thermal analysis to determine the most suitable calcination temperature to apply to the materials and indicate the steps involved in obtaining Ag-doped ceria. Scanning electron microscopy images revealed small crystallite sizes, the presence of oxygen vacancies, structural stability and homogeneity. The Ag-doped ceria have shown effective and efficient antimicrobial activity, inhibiting the growth of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa bacteria. However, pure CeO2 displayed no antibacterial activity. Therefore, the satisfactory antimicrobial activity reported here can be attributed to the partial substitution of cerium ions by silver ions.

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Acknowledgements

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001. The authors acknowledge the support of the Brazilian research funding agencies CAPES/PROCAD: Process No. 2013/2998/2014 (Federal Agency for the Support and Improvement of Higher Education/National Program of Academic Cooperation) and CNPq Process Nos. 485518/2013-9 and 307054/2015-2 (National Council for Scientific and Technological Development).

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Authors and Affiliations

  1. Departamento de Química, Universidade Federal de Goiás, Catalão, GO, 75704-020, Brazil

    Murillo Henrique de Matos Rodrigues, Kellen Cristina Mesquita Borges, Maria Rita de Cássia Santos, Rosana de Fátima Gonçalves & Mario Godinho Jr.

  2. Departamento de Ciências Biológicas, Universidade Federal de Goiás, Catalão, GO, 75704-020, Brazil

    Jupyracyara Jandyra de Carvalho Barros

  3. Departamento de Engenharia de Materiais, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil

    Fabiana Villela Motta

  4. Graduate Program in Materials Science and Engineering, Federal University of Pelotas, Gomes Carneiro, 1, Pelotas, RS, CEP 96010-000, Brazil

    Neftali L. V. Carreno

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  1. Murillo Henrique de Matos Rodrigues
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de Matos Rodrigues, M.H., Borges, K.C.M., de Cássia Santos, M.R. et al. Synthesis, characterization and in vitro antimicrobial prospecting of silver-doped ceria. J Therm Anal Calorim 139, 849–854 (2020). https://doi.org/10.1007/s10973-019-08506-z

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