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Experimental study on the energetics of two indole derivatives

Standard molar enthalpies of formation of indole-2-carboxylic acid and indole-3-carboxaldehyde

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Abstract

The standard (p o = 0.1 MPa) molar energies of combustion, \( \Updelta_{\text{c}} H_{\text{m}}^{\text{o}} \), for indole-2-carboxylic acid and indole-3-carboxaldehyde, in the crystalline state, were determined, at T = 298.15 K, using a static bomb combustion calorimeter. For both compounds, the vapour pressures as function of temperature were measured, by the Knudsen effusion technique, and the standard molar enthalpies of sublimation, \( \Updelta_{\text{cr}}^{\text{g}} H_{\text{m}}^{\text{o}} \), at T = 298.15 K, were derived by the Clausius–Clapeyron equation. From the experimental results, the standard (p o = 0.1 MPa) molar enthalpies of formation in the condensed and gaseous phases, at T = 298.15 K, of indole-2-carboxylic acid and indole-3-carboxaldehyde were derived. The results are analysed in terms of structural enthalpic increments.

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Acknowledgements

Thanks are due to Fundação para a Ciência e Tecnologia (FCT), Lisbon, Portugal and to FEDER for financial support given to Centro de Investigação em Química da Universidade do Porto and to Programa Ciência 2008 (PEst-C/QUI/UI0081/2011). Joana I. T. A. Cabral thanks FCT for the award of a Post-Doc research grant (SFRH/BPD/64735/2009).

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  1. Joana I. T. A. Cabral

    Present address: LEPAE, Chemical Engineering Department, Faculty of Engineering, University of Porto, Rua Roberto Frias, 4200-465, Porto, Portugal

Authors and Affiliations

  1. Department of Chemistry and Biochemistry, Faculty of Science, Centro de Investigação em Química, University of Porto, Rua do Campo Alegre, 687, 4169-007, Porto, Portugal

    Luísa M. P. F. Amaral, Tânia M. T. de Carvalho, Joana I. T. A. Cabral, Maria D. M. C. Ribeiro da Silva & Manuel A. V. Ribeiro da Silva

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  1. Luísa M. P. F. Amaral
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Correspondence to Maria D. M. C. Ribeiro da Silva.

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Amaral, L.M.P.F., de Carvalho, T.M.T., Cabral, J.I.T.A. et al. Experimental study on the energetics of two indole derivatives. J Therm Anal Calorim 115, 803–810 (2014). https://doi.org/10.1007/s10973-013-3332-8

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