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Synthesis, spectral characterisation and thermal studies of zirconyl complexes of biologically active molecules

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Abstract

Zirconyl complexes of hippuric acid (C9H9NO3, hipH) and monophenylbutazone (4-butyl-1-phenyl-3,5-pyrazolidinedione, MPB) were prepared using ZrOCl2 · 8H2O and ZrO(NO3)3 · xH2O and characterized by elemental analysis, molar conductance measurement and IR, UV–Vis and NMR spectral methods. Thermal decomposition behaviour was studied by thermogravimetry. The second harmonic generation (SHG) conversion efficiency of hippuric acid complexes was also studied.

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References

  1. Capllonch MC, Garcia-Raso A, Terron A, Apella MC, Espinosa E, Molins E. Interactions of d10 metal ions with hippuric acid and cytosine X-ray structure of the first cadmium (II)-amino acid derivative-nucleobase ternary compound. J Inorg Biochem. 2001;85:173–8.

    Article  CAS  Google Scholar 

  2. Sgarabotto P, Bisceglie F, Pelosi G, Abdel-Rahman L. Synthesis, x-ray crystal structures and characterization of copper(II)-2,2’-bipyridyl derivatives of (4-amino)-hippuric acid and of L-proline. Polyhedron. 1999;8:2505–10.

    Article  Google Scholar 

  3. Terron A, Fiol JJ, Herrero LA, Garcia-Rasso A, Apella MC, Caubet A, et al. Metal-amino acid (or peptide)-nuclesoide (or related bases) ternary complexes. An Quim Int Ed. 1997;93:60–7.

    CAS  Google Scholar 

  4. Garcia-Raso A, Fiol JJ, Adrover B, Moreno V, Molins E, Mata L. Synthesis and structure of isocytosine ternary copper(II) complexes. Dalton Trans J Chem Soc. 1998;1031–6.

  5. Ashby CIH, Paton WF, Brown TL. Nitrogen-14 nuclear quadrupole resonance spectra of the coordinated amino group and of coordinated imidazole. Crystal and molecular structures of chloroglycylglycinato(imidazole)cadmium. J Am Chem Soc. 1980;102:2990–8.

    Article  CAS  Google Scholar 

  6. Morelock MM, Good ML, Trefonas LM, Karraker DG, Maleki L, Eichelberger HR, et al. Metal ion complexes of alpha amino acids. Structure and magnetic properties of the nickel and cobalt hippurates. Pseudo-one-dimensional magnetic systems. J Am Chem Soc. 1979;101:4858–66.

    Article  CAS  Google Scholar 

  7. Grewe H, Udupa MR, Kerbs B. Crystal and molecular structure of bis(N-benzoylglycinato)triaquozinc(II) dihydrate. Inorg Chim Acta. 1982;63:119–24.

    Article  CAS  Google Scholar 

  8. Brzyska W, Hakim M. Thermal decomposition of Co(II), Ni(II), Cu(II) and Zn(II) hippurates. J Therm Anal Calorim. 1990;36:847–53.

    Google Scholar 

  9. Brzyska W, Hakim M. Thermal decomposition of Y, La and light lanthanide complexes of hippuric acid. J Therm Anal. 1988;34:47–53.

    Article  CAS  Google Scholar 

  10. Refat MS, Teleb SM, Sadeek SA, Khater HM, El-Megharbel SM. Synthesis and characterization of some hippurato rare earth metal complexes. J Kor Chem Soc. 2005;49:3261–68.

    Google Scholar 

  11. Sadeek SA, Refat MS, Teleb SM, Megharbel EI. Synthesis and characterization of V(III), Cr(III) and Fe(III) hippurates. J Mol Struct. 2005;737:139–45.

    Article  CAS  Google Scholar 

  12. Allan JR, Dalrymple J. The thermal, spectral and magnetic studies of hippuric acid compounds of cobalt (II), nickel (II), copper (II) and zinc (II) ions. Thermochim Acta. 1991;185:83–9.

    Article  Google Scholar 

  13. Khayyal MT, El-Ghazaly M, El-Khatib AS, Hatem A. Tolerability of mofebutazone in asthmatic patients. Int J Clin Pharmacol Res. 1995;15:145–51

    CAS  Google Scholar 

  14. Paradies HH, Ziedrich KH, Hans H, Flaeming. Zur-keto-enol-tomtomerie von 1-phenyl 4n-butyl-pyrazolidin-(3,5)dion. Acta Pharm Technol. 1987;33:180–8.

    CAS  Google Scholar 

  15. Suma S, Sudarsanakumar MR, Nair CGR, Prabhakaran CP. Synthesis and characterization of chromium(III), manganese(III), iron(III), cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II) and mercury(II) complexes of monophenylbutazone. Indian J Chem. 1994;33A:1107–9.

    CAS  Google Scholar 

  16. Kurtz SK, Perry TT. A powder technique for the evaluation of nonlinear optical materials. J Appl Phys. 1968;39:3798–813.

    Article  CAS  Google Scholar 

  17. Kumar G, Srivastava M. Spectral and magnetochemical studies of nickel(II) and cobalt(II) complexes of hippuric acid. Rev Chim Miner. 1979;16:14–8.

    CAS  Google Scholar 

  18. Nakamoto K. Infrared and Raman spectra of inorganic and coordination compounds. 4th ed. New York: Wiley; 1986.

    Google Scholar 

  19. Refat MS, EI Korashy SA, Ahmed S. Synthesis and characterization of Mn(II), Au(III) and Zr(IV) hippurates complexes. Spectrochim Acta Part A Biomol Spectrosc. 2008;70:840–9.

    Article  Google Scholar 

  20. Drożdż-Cieśla E, Małecki A. Mechanism of thermal decomposition of zirconyl oxalate ZrOC2O4. J Therm Anal Calorim. 2008;92:939–44.

    Article  Google Scholar 

  21. Coats AW, Redfern JP. Kinetic parameters from thermogravimetric data. Nature. 1964;201:68–9.

    Article  CAS  Google Scholar 

  22. MacCallum JR, Tanner. The kinetics of thermogravimetry. J Eur Polym. 1970;6:1033–7.

    Article  CAS  Google Scholar 

  23. Muraleedharan Nair MK, Radhakrishnan PK. Thermal decomposition kinetics of lanthanum complexes of 1,2-(Diimino-4’-Antipyrinyl)ethane. Thermochim Acta. 1997;292:115–22.

    Article  Google Scholar 

  24. Thankamony M, Sindhu Kumari B, Rijulal G, Mohanan K. Lanthanum(III) chloride complexes with heterocyclic Schiff bases. J Therm Anal Calorim. 2009;95:259–66.

    Article  CAS  Google Scholar 

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Acknowledgements

The authors are grateful to the authorities of the SAIF, Cochin University of Science and Technology, and SAIF, IIT Chennai, for providing the instrumental facilities. We are also grateful to Prof P.K. Das, Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, for NLO studies. S.S is grateful to UGC for financial assistance and J.K.R is thankful to University of Kerala for the award of a fellowship.

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Authors and Affiliations

  1. Department of Chemistry, S.N. College, Kollam, Kerala, India

    K. R. Jisha & S. Suma

  2. Department of Chemistry, M.G College, Thiruvananthapuram, Kerala, India

    M. R. Sudarsanakumar

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  1. K. R. Jisha
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  2. S. Suma
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  3. M. R. Sudarsanakumar
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Correspondence to S. Suma.

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Jisha, K.R., Suma, S. & Sudarsanakumar, M.R. Synthesis, spectral characterisation and thermal studies of zirconyl complexes of biologically active molecules. J Therm Anal Calorim 99, 509–513 (2010). https://doi.org/10.1007/s10973-009-0432-6

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  • DOI: https://doi.org/10.1007/s10973-009-0432-6

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