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Preparation and characterization of mikania micrantha (MM)/chitosan (CS) nanocomposites with polyvinyl alcohol (PVA) back layer

  • Original Paper: Nano-structured materials (particles, fibers, colloids, composites, etc.)
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Abstract

In this study, we present the formation of mikania micrantha (MM)/chitosan (CS) electrospun nanocomposites using polyvinyl alcohol (PVA) back layer. The therapeutic compounds of MM were extracted through a methanol extraction process. Results show that the nanocomposites exhibit antibacterial activity against gram-positive (S. aureus) and gram-negative (E. coli) bacteria, with a zone of inhibition of around 20–25 mm. MM-2/CS was found to be more effective than MM-1/CS due to the increased amount of MM extraction. The nanofibers exhibited smooth fiber formation with a mean diameter of around 173–185 nm as observed by SEM. Moreover, the incorporation of PVA with MM-chitosan nanocomposites improved their thermal and moisture management properties. Cytotoxicity test showed that only around 5% of the exposed cells survived in the Vero cell line. The FTIR spectra demonstrated the presence of functional groups of PVA, chitosan, and MM in the nanofibers. Based on our findings, we suggest that nanofibers prepared from bioactive agents of MM may have the potential for biomedical applications, such as wound dressing materials.

Graphical Abstract

Highlights

  • Biobased antibacterial nanofibers for potential biomedical applications.

  • Plant extract (Mikania micrantha) was employed in biopolymers for electrospinning.

  • Smooth fiber formation was observed by SEM analysis.

  • Prepared nanocomposites demonstrated good mechanical, absorbance, and antibacterial properties.

  • PVA back layer improved the overall properties of nano mat.

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Acknowledgements

Immense gratitude goes to the Department of Textile Engineering, DUET, for providing lab facilities.

Author contributions

CRediT authorship contribution statement. MdNU: Concept generation, experimental, drafted manuscript. MdM: Experimental and proofread. SMI: Experimental, proofread. MdJ: Raw material collection and proofread. SIM: Proofreading and correction. AA: Supervised the work, edited, and proofread.

Funding

The research team did not receive grants or funds from any public, private, or commercial organizations.

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Authors and Affiliations

  1. Department of Textile Engineering, Dhaka University of Engineering & Technology (DUET), Gazipur, Bangladesh

    Md Nur Uddin, Md. Mohebbullah, Syed Maminul Islam & Ayub Ali

  2. Department of Electrical and Electronic Engineering, Northern University Bangladesh, Dhaka, Bangladesh

    Md. Jobaer

  3. Eastern Medical College, Comilla, Bangladesh

    Sajjatul Islam Mahedi

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  1. Md Nur Uddin
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  2. Md. Mohebbullah
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  3. Syed Maminul Islam
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Uddin, M.N., Mohebbullah, M., Islam, S.M. et al. Preparation and characterization of mikania micrantha (MM)/chitosan (CS) nanocomposites with polyvinyl alcohol (PVA) back layer. J Sol-Gel Sci Technol 108, 84–97 (2023). https://doi.org/10.1007/s10971-023-06182-y

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