Abstract
This research presents a synthesis process of porous α-MoO3 wire from Mo wire and its application as an irradiation target used in the Dalat Nuclear Research Reactor (DNRR) for the first time. Water was used to extract 99Mo in the porous wire after irradiating, afterward, the result was compared with a previous experiment using α-MoO3 powder. In conclusion, combined with the Kyoto University Reactor (KUR) experiments, hot atoms ehnanced the extraction of 99Mo to water and the effectiveness in the porous wire was compared to that of commercial powder.
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Pillai M, Dash A, Knapp F (2013) Sustained availability of 99mTc: possible path forward. J Nucl Med 54(2):313–323
National Research Council (US) Committee on Medical Isotope Production Without Highly Enriched Uranium. (2009) Medical Isotope Production without Highly Enriched Uranium. Washington (DC) 18p. National Academies Press (US); https://www.ncbi.nlm.nih.gov/books/NBK215149/
Lyra M, Charalambatou P, Roussou E, Fytros S, Baka I (2011) Alternative production methods to face global molybdenum-99 supply shortage. Hell J Nucl Med. 14(1):49–55. Available from: https://pubmed.ncbi.nlm.nih.gov/21512666/.
Hippel FV (2016) Banning the production of highly enriched uranium. Research report No. 15, International Panel on Fissile Materials.
Public-Private Investigative Commission (2011) Action plans for the stable supply of 99mTc in Japan. http://wwwa.cao.go.jp/oaep/mo-supply/houkokusho
Proposal for the stable supply organization of the radioisotope in Japan, Subcommittee in science council of Japan. http://www.scj.go.jp/ja/info/kohyo/pdf/kohyo-20-t60-5, 2008.
Hetherington ELR, Boyd RE (1999) Targets for the production of neutron activated molybdenum-99. In production technologies of molybdenum-99 and technetium-99m. Int At. Energy Agency, Report No. IAEA-TECDOC-1065
Nishikata K, Kimura A, Ishida T, Tsuchiya K, Shiina T, Ohta A, Tanase M (2014) Fabrication technology development and characterization of irradiation targets for 99Mo/99mTc production by (n, γ) method. Japan Atomic Energy Agency, Report No. JAEA-Technology-2014–034
Dodbiba G, Wu IC, Lee YC, Matsuo S, Toyohisa F (2010) Adsorption of molybdenum ion in nitric acid solution by using a Pb-Fe based. J Soc Mater Eng Res 17(1):28–34
Ilyin AP, Korovin SA, Menshikov LI, Petrunin VF, Semenov AN, Chuvilin DY (2015) Usage of molybdenum nanocrystalline powder for radioisotope production. Phys Pro 72:548–551
Ma C, Vasileiadis A, Wolterbeek H, Denkova A, Crespo P (2022) Adsorption of molybdenum on Zr-based MOFs for potential application in the 99Mo/99mTc generator. Appl Surf Sci 572:151340
Nishikata K, Kimura A, Shiina T (2013) Fabrication and characterization of high-density MoO3 pellets. In: Proceeding of 2012 Powder metallurgy world congress and exhibition (PM 2012), Yokoham (Japan), (CD-ROM)
Kimura A, Sato Y, Tanase M, Tsuchiya M (2011) Development of high density MoO3 pellets for production of 99Mo medical isotope. IOP Conf Ser: Mater Sci Eng 18:042001
Suematsu H, Sato S, Nakayama T, Suzuki T, Niihara K, Nanko M, Tsuchiya K (2020) Two-step-pressurization method in pulsed electric current sintering of MoO3 for production of 99mTc radioactive isotope. J of Asian Cer Soc 8(4):1154–1161
Le VS (2014) Generator development: up-to-date recovery technologies for increasing the effectiveness of utilisation. Sci Tech of Nucl Inst. Article ID 345252
Hasan S, Prelas MA (2020) Molybdenum-99 production pathways and the sorbents for 99Mo/99mTc generator systems using (n, γ) 99Mo: a review. SN Appl Sci. Article No. 1782.
Matyskin AV, Ridikas D, Skuridin VS, Sterba J, Steinhauser G (2013) Feasibility study for production of 99mTc by neutron irradiation of MoO3 in a 250 kW TRIGA Mark II reactor. J Radioanal Nucl Chem 298(1):413–418
Suematsu H, Seki M, Suzuki T (2020) Method for producing radioisotope Mo-99 and target material. Japan Patent Office
Tran QT (2020) Development of porous MoO3 targets for production/separation of radioisotopes with water. Master thesis. Nagaoka Univ. Tech.
Tachimor S, Nakamura H, Amano H (1971) Diffusion of Tc-99m in neutron irradiated molybdenum trioxide and its application to separation. J Nucl Sci Tech 8(6):295–301
Choppin G, Liljenzin JO, Rydberg J, Ekberg C (2012) Radiochemistry and nuclear chemistry chapter 17, 4th edn. Academic Press, Oxford
Lieser KH, Kratz JV (2007) Nuclear and radiochemistry: fundamentals and applications, 2nd edn. Wiley KAH, Weinheim
Blaauw M, Ridikas D, Baytelesov S, Bedregal Salas PS, Chakrova Y, Cho EH, Dahalan R, Fortunato AH, Jacimovic R, Kling A, Muñoz L, Mohamed NMA, Párkányi D, Singh T, Duong VD (2017) Estimation of 99Mo production rates from natural molybdenum in research reactors. J Rad Nucl Chem 311:409–418
Budavari S, O’Neil MJ, Smith A, Heckelman PE (1989) The Merck index: an encyclopedia of chemicals, drugs, and biologicals, 11th edn. Merck and Co Inc, Rahway
Toth JJ, Greenwood LR, Soderquist CZ, Wittman RS, Pierson BD, Burns KA, Lavender CA, Painter CL, Love EF, Wall DE (2011) Production of molybdenum-99 using neutron capture methods. United States Department of Energy: U.S. Department of Energy
Tachibana Y, Yamazaki Y, Nomura M, Suzuki T (2015) Molybdenum isotope fractionation in ion exchange reaction by using anion exchange chromatography. J Rad Nucl Chem 303(2):1429–1434
Acknowledgements
The research has been supported by GAICCE Double Degree Scholarship from ASEAN University Network/Southeast Asia Engineering Education Development Network (AUN/SEED-net) and KAKENHI-PROJECT-19H02429. In the experiments at KUR, the authors acknowledge Ms. M. Seki at Japan Atomic Energy Agency, Mr. Y. Fujihara and Prof. S. Fukutani at Kyoto University for their help in irradiation preparations and ICP-MS measurements.
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Japan Society for the Promotion of Science
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Quach, N.M., Ngo, M.C., Yang, Y. et al. Extraction of 99Mo hot atoms made by a neutron capture method from α-MoO3 to water. J Radioanal Nucl Chem 332, 4057–4064 (2023). https://doi.org/10.1007/s10967-023-09125-7
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DOI: https://doi.org/10.1007/s10967-023-09125-7