Abstract
In-house reference material (IRM) cocoa powder (CCP) has been in use at US Food and Drug Administration laboratories for about 15 years. A single lot of commercial material was originally characterized for 32 elements by several laboratories and five techniques. A unique approach for basis weight determination based upon ambient relative humidity was developed for CCP, eliminating the need for dry weight determinations. The CCP Reference Sheet is updated by incorporating new results approximately every 5 years. The last update occurred in 2006. As part of an effort to revalidate and update values for CCP, anticoincidence instrumental neutron activation analysis (INAA) was used to determine mass fractions for 16 of the originally characterized elements, as well as to provide information on 16 other elements. Results were in very good agreement with 2006 Reference Sheet values. A new candidate IRM, fresh-frozen swordfish (FFSF) powder, was produced by adding inorganic As, Cd, Cr, Hg, Pb, Sb, and Se to liquid nitrogen-frozen commercial swordfish filets which were then homogenized. Portions of FFSF were analyzed by INAA to provide mass fraction and homogeneity information for As, Cd, Cr, Hg, Sb, and Se as well as for eight other elements occurring naturally in the material. Non-homogeneities were ≤2.5 % for As, Br, Cd, and Cs, and ≤1.8 % for Cr, Hg, Rb, Sb, and Se. Certified reference materials DORM-3 Fish Protein powder and fresh-frozen SRM 1947 Lake Michigan Fish Tissue were analyzed as controls.
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References
Total Diet Study (2010) U. S. Food and Drug Administration, Rockville. http://www.fda.gov/Food/FoodSafety/FoodContaminantsAdulteration/TotalDietStudy/default.htmAccessed 19 Dec 2011
Anderson DL, Cunningham WC (1994) Trans Am Nucl Soc 71:21
Cunningham WC, Anderson DL (1999) Characterization and use of cocoa powder in-house reference material, Abstract 197, MTAA-10, Bethesda: 311
Cunningham WC (2006) Reference sheet for FDA cocoa powder reference material, U. S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park
Zeisler R, Langland JK, Harrison SH (1983) Anal Chem 55:2431–2434
Anderson DL (2009) J Radioanal Nucl Chem 282(1):11–14
Anderson DL (2009) J Radioanal Nucl Chem 282(1):75–79
Lindstrom RM, Zeisler R, Mackey EA, Popelka-Filcoff RS, Williams RE (2008) J Radioanal Nucl Chem 278(1):665–669
Currie LA (1968) Anal Chem 40(1):586–593
Thompson M, Wood R (1993) J AOAC Int 76:926–940
Hight SC, Cheng J (2006) Anal Chim Acta 567(2):160–172
Keith LH, Crummett W, Degan J, Libby RA, Taylor JK, Wentler G (1983) Anal Chem 55:2210–2218
Certificate of Analysis, SRM 1947 (2007) National Institute of Standards and Technology, Gaithersburg
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The authors are indebted to the reactor operations staff at the NCNR for their valuable contributions to this work.
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Anderson, D.L., Cunningham, W.C. Analysis of FDA in-house food reference materials with anticoincidence INAA. J Radioanal Nucl Chem 296, 175–180 (2013). https://doi.org/10.1007/s10967-012-1931-7
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DOI: https://doi.org/10.1007/s10967-012-1931-7