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Design calculations of an accelerator based BSA for BNCT of brain cancer

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Abstract

Monte Carlo simulations were carried out to calculate optimum design parameters of an accelerator based Beam Shaping Assembly (BSA) for Boron Neutron Capture Therapy (BNCT) of Brain Cancer setup. Epithermal beam of neutrons were obtained through moderation fast neutrons from 7Li(p,n) reaction in a high density polyethylene moderator and a graphite reflector. The dimensions of the moderator and the reflector were optimized through optimization of epithermal/fast neutron intensity ratio as a function of geometric parameters of the setup. Results of our calculation showed the capability of our setup to treat the tumor within 4 cm of the head surface. The calculated Peak Therapeutic Ratio for the setup was found to be 2.15. With further improvement in the polyethylene moderator design and brain phantom irradiation-arrangement, the setup capabilities can be improved to reach further deep-seated tumor.

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Authors and Affiliations

  1. Department of Physics, King Fahd University of Petroleum and Minerals, Dhahran, 31261, Saudi Arabia

    B. A. Elshahat, A. A. Naqvi & Khalid Abdalla

Authors
  1. B. A. Elshahat
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  2. A. A. Naqvi
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  3. Khalid Abdalla
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Correspondence to A. A. Naqvi.

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Elshahat, B.A., Naqvi, A.A. & Abdalla, K. Design calculations of an accelerator based BSA for BNCT of brain cancer. J Radioanal Nucl Chem 274, 539–544 (2007). https://doi.org/10.1007/s10967-006-6949-2

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  • DOI: https://doi.org/10.1007/s10967-006-6949-2

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