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Investigation of the synthesis and properties of the copolymeric hydrogels based on N-isopropyl acrylamide and acrylamidoazobenzene

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Abstract

A series of copolymers and their corresponding hydrogels were prepared essentially from N-isopropyl acrylamide (NIPAAm) and acrylamidoazobenzene (AAAB) at different molar ratios. The AAAB was synthesized in advance and verified by elemental analysis, 1H-, and 13C NMR techniques. The effect of AAAB contents on the thermal and ultraviolet response of the copolymer and their corresponding hydrogels was investigated. The results showed that a changed quantity of AAAB in the copolymers and hydrogels would only slightly affect their LCSTs and CGTTs. In addition, the copolymers and their hydrogels show good thermo- and photo-response due to NIPAAm structure and the cis-trans isomerization of azobenzene group upon UV irradiation. Furthermore, effects of AAAB contents on the physical properties and drug release behavior of the copolymeric hydrogels were also examined.

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Acknowledgments

The authors would like to thank Dr. Ta-Hsien Lin in the Veterans General Hospital at Taipei for the technical support of NMR facility. The authors would also thank the Tatung University for their financial support under Grant B 100-C01-017.

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Authors and Affiliations

  1. Department of Chemical Engineering, Tatung University, Taipei, 10451, Taiwan

    Yan-Su Lin & Wen-Fu Lee

  2. Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan

    Chao-Hsiung Lin

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  1. Yan-Su Lin
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  2. Chao-Hsiung Lin
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Correspondence to Wen-Fu Lee.

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Lin, YS., Lin, CH. & Lee, WF. Investigation of the synthesis and properties of the copolymeric hydrogels based on N-isopropyl acrylamide and acrylamidoazobenzene. J Polym Res 21, 364 (2014). https://doi.org/10.1007/s10965-014-0364-0

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  • DOI: https://doi.org/10.1007/s10965-014-0364-0

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