Skip to main content
SpringerLink
Log in

Synthesis and micellization of P(NIPAM-co-HMAM)-b-PEO-b-P(NIPAM-co-HMAM) triblock copolymers

  • Original Paper
  • Published:
Journal of Polymer Research Aims and scope Submit manuscript

Abstract

Temperature-responsive P(NIPAM-co-HMAM)-b-PEO-b-P(NIPAM-co-HMAM) triblock copolymers were synthesized by an atomic transfer radical polymerization (ATRP) method without freeze–pump–thaw cycles. The composition, structure, and molecular weight of the synthesized block copolymer were characterized by 1 H NMR and GPC. The phase transitions induced by temperature for different copolymers in dilute aqueous solutions have been studied using transmittance measurements, laser particle size measurements, viscosity analysis, and surface tension measurement, which showed that the HMAM content and the PEO (or PEG) chain length in the synthesized triblock copolymer affects the copolymer’s lower critical solution temperature (LCST). The micellization behavior of each temperature-responsive triblock copolymer was investigated by fluorescence probe measurements and transmission electron microscopy (TEM), which showed that the triblock copolymers form stable micelles above the LCST. The introduction of the HMAM component and the formation of micelles represent the first steps in the development of an injectable gel that forms in situ through chemical and physical crosslinking.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme 1
Scheme 2
Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  1. Poe GD, Jarrett WL, Scales CW, McCormick CL (2004) Macromolecules 37:2603–2612

    Article  CAS  Google Scholar 

  2. Janne V, Arotcüaréna M, Heise B, Ishaya S, Laschewsky A, Tenhu H (2002) Langmuir 18:5360–5363

    Article  Google Scholar 

  3. Gil ES, Hudson SM (2004) Prog Polym Sci 29:1173–1222

    Article  CAS  Google Scholar 

  4. Tanaka Y, Gong JP, Osada Y (2005) Prog Polym Sci 30:1–9

    Article  CAS  Google Scholar 

  5. Sukhorukov G, Fery A, Möhwald H (2005) Prog Polym Sci 30:885–897

    Article  CAS  Google Scholar 

  6. Dobrynin AV, Rubinstein M (2005) Prog Polym Sci 30:1049–1118

    Article  CAS  Google Scholar 

  7. Rusu M, Wohlrab S, Kuckling D, Möhwald H, Schönhoff M (2006) Macromolecules 39:7358–7363

    Article  CAS  Google Scholar 

  8. Wei H, Cheng SX, Zhang XZ, Zhuo RX (2009) Prog Polym Sci 34:893–901

    Article  CAS  Google Scholar 

  9. Hai XC, Xie SA, Zhou YF, Huang W, Yan DY, Yang JT, Ji B (2010) J Phys Chem B 114:6291–6299

    Article  Google Scholar 

  10. Sistach S, Beija M, Rahal V, Brûlet A, Marty JD, Destarac M, Mingotaud C (2010) Chem Mater 22:3712–3724

    Article  CAS  Google Scholar 

  11. O’Lenick TG, Jiang XG, Zhao B (2010) Langmuir 26:8787–8796

    Article  Google Scholar 

  12. Miyazawa K, Winnik FM (2002) Macromolecules 35:9536–9544

    Article  CAS  Google Scholar 

  13. Wei H, Wu DQ, Li Q, Chang C, Zhou JP, Zhang XZ, Zhuo RX (2008) J Phys Chem C 112:15329–15334

    Article  CAS  Google Scholar 

  14. Matyjaszewski K, Xia JH (2001) Chem Rev 101:2921–2990

    Article  CAS  Google Scholar 

  15. Kamigaito M, Ando T, Sawamoto M (2001) Chem Rev 101:3689–3745

    Article  CAS  Google Scholar 

  16. Wei H, Chen WQ, Chang C, Cheng C, Cheng SX, Zhang XZ, Zhuo RX (2008) J Phys Chem C 112:2888–2894

    Article  CAS  Google Scholar 

  17. Reddy MP, Venkatesu P (2011) J Phys Chem B 115:4752–4757

    Article  CAS  Google Scholar 

  18. Kelarakis A, Tang T, Havredaki V, Viras K, Hamley IW (2008) J Colloid Interface Sci 320:70–73

    Article  CAS  Google Scholar 

  19. Rao JY, Luo ZF, Ge ZS, Liu H, Liu SY (2007) Biomacromolecules 8:3871–3878

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This research was supported by financial support from the National Natural Science Foundation of China (20973106), the Fundamental Research Funds for the Central Universities of China (GK201001001), and the Program for Changjiang Scholars and Innovative Research Team in University of China (IRT1070).

Author information

Authors and Affiliations

  1. Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an, 710062, People’s Republic of China

    Wei-Na Yu, Shou-Xin Liu, Hong-Mei Wang & Rong Tian

Authors
  1. Wei-Na Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shou-Xin Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hong-Mei Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rong Tian
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shou-Xin Liu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yu, WN., Liu, SX., Wang, HM. et al. Synthesis and micellization of P(NIPAM-co-HMAM)-b-PEO-b-P(NIPAM-co-HMAM) triblock copolymers. J Polym Res 19, 9989 (2012). https://doi.org/10.1007/s10965-012-9989-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10965-012-9989-z

Keywords

Search

Navigation