Abstract
A biodegradable elastomer (PLCA/PLGA blends) was prepared and characterized. First, poly(DL-lactide-co-ε-caprolactone) (PLCA) and poly(DL-lactide-co-glycolide) (PLGA) were synthesized. Infrared (IR) spectroscopy, 1H nuclear magnetic resonance (NMR), and gel permeation chromatography (GPC) were used to confirm the formation and structure of PLCA and PLGA. The solubility parameters of PLCA and PLGA were measured to estimate the miscibility between them. A series of PLCA/PLGA blends was prepared through solution blending. The morphology of all blends was examined by scanning electron microscope (SEM), and no obvious phase separation was detected at various ratios of PCLA and PLGA. Thermomechanical properties were characterized using thermogravimetry (TG), differential scanning calorimetry (DSC), and dynamic mechanical analysis (DMA), the results showed that the PLCA/PLGA blends were a type of immiscible but compatible polymer blend. Mechanical properties, particularly stress-strain behavior, were examined; with an increase in PLGA content, the tensile strength and Young’s modulus of the blends increased dramatically, while elongation at break decreased.
Similar content being viewed by others
References
Wu DF, Zhang YS, Zhang M, Zhou WD (2008) Eur Polym J 44:2171. doi:10.1016/j.eurpolymj.2008.04.023
Duan B, Yuan XY, Zhu Y, Zhang YY, Li XL, Zhang Y, Yao KD (2006) Eur Polym J 42:2013. doi:10.1016/j.eurpolymj.2006.04.021
Benali S, Peeterbroeck S, Brocorens P, Monteverde F, Bonnaud L, Alexandre M, Lazzaroni R, Dubois P (2008) Eur Polym J 44:1673. doi:10.1016/j.eurpolymj.2008.03.020
Bhattarai N, Bhattarai SR, Khil MS, Lee DR, Kim HY (2003) Eur Polym J 39:1603. doi:10.1016/S0014-3057(03)00057-0
Ding CF, Wang Y, Zhang SS (2007) Eur Polym J 43:4244. doi:10.1016/j.eurpolymj.2007.07.032
Cohn D, Salomon AH (2005) Biomaterials 26:2297. doi:10.1016/j.biomaterials.2004.07.052
Wang M, Chen W, Zhang H, Li XL, Zhang Y, Yao KD, Yao FL (2007) Eur Polym 43:4683. doi:10.1016/j.eurpolymj.2007.08.012
Garkhal K, Verma S, Jonnalagadda S, Kumar NJ (2007) Polym Sci Part A Polym Chem 45:2755. doi:10.1002/pola.22031
Huang MH, Li S, Vert M (2004) Polymer (Guildf) 45:8675. doi:10.1016/j.polymer.2004.10.054
Wang WS, Ping P, Yu HJ, Chen XS, Jing XB (2006) J Polym Sci Part Polym Chem 44:5505. doi:10.1002/pola.21643
Rezgui F, Swistek M, Hiver JM, G’Sell C, Sadoun T (2005) Polymer 46:7370. doi:10.1016/j.polymer.2005.03.116
Teramoto N, Urata K, Ozawa K, Shibata M (2004) Polym Degrad Stabil 86:401. doi:10.1016/j.polymdegradstab.2004.04.026
Chen CC, Chueh JY, Tseng H, Huang HM, Lee SY (2003) Biomaterials 24:1167. doi:10.1016/S0142-9612(02)00466-0
Domb AJ (1993) J Polym Sci Part Polym Chem 31:1973. doi:10.1002/pola.1993.080310805
Apohan NK, Akdemir ZS (2005) Polym Adv Technol 16:807. doi:10.1002/pat.656
Jaczewska J, Raptis I, Budkowski A, Goustouridis D, Raczkowska J, Sanopoulou M, Pamula E, Bernasik A, Rysz J (2007) Synth Met 157:726. doi:10.1016/j.synthmet.2007.07.015
Ravindra R, Krowidi KR, Khan AA (1998) Carbohydr Polym 36:121. doi:10.1016/S0144-8617(98)00020-4
Schenderlein S, Luck M, Muller BW (2004) Int J Pharm 286:19. doi:10.1016/j.ijpharm.2004.07.034
Roberts RJ, Rowe RC (1993) Int J Pharm 99:157. doi:10.1016/0378-5173(93)90357-L
Adamska K, Voelkel A (2005) Int J Pharm 304:11. doi:10.1016/j.ijpharm.2005.03.040
Robin HB, Liu JC, Chien YW (1988) Int J Pharm 42:199. doi:10.1016/0378-5173(88)90176-7
Wu PX, Zhang LC (1996) Blends and modification of polymers. China Light Industry, Beijing
Utracki LA (1989) Polymer alloys and blends, thermodynamic and rheology. Hanser, Munich
Mark HF (2004) Encyclopedia of polymer science and technology. Wiley, New York
Averous L, Moro L, Dole P (2000) Polymer (Guildf) 41:4157. doi:10.1016/S0032-3861(99)00636-9
Acknowledgments
This project is financially supported by the key sci-tech special projects and programs for prior topics from Science and Technology Department of Zhejiang Province, China (2008C11126).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Wang, L., Zhang, Z., Chen, H. et al. Preparation and characterization of biodegradable thermoplastic Elastomers (PLCA/PLGA blends). J Polym Res 17, 77–82 (2010). https://doi.org/10.1007/s10965-009-9292-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10965-009-9292-9